Department of Applied Chemistry, Kyung Hee University, Yongin, Gyeonggi 446-701, South Korea.
Analyst. 2017 Jun 26;142(13):2372-2377. doi: 10.1039/c7an00356k.
This paper examines the effect of polydopamine (PD) coating of gold nanorods (GNRs) on their performance as a matrix material for laser desorption/ionization time-of-flight mass spectrometry (LDI-TOF-MS) analysis. Bare GNRs and PD-coated GNRs (PD@GNRs) were utilized for LDI-TOF-MS analyses of small molecules and synthetic polymers, and the influences of PD-coating were mechanistically studied. Based on the results, we found that the PD-coating of GNRs suppressed the generation of undesired gold cluster ions, enhanced photothermal conversion and the LDI-TOF-MS efficiency, and expanded the working molecular weight range.
本文研究了聚多巴胺（PD）涂层金纳米棒（GNRs）对其作为基质材料用于激光解吸/电离飞行时间质谱（LDI-TOF-MS）分析的性能的影响。本文利用裸 GNRs 和 PD 涂层 GNRs（PD@GNRs）对小分子和合成聚合物进行了 LDI-TOF-MS 分析，并从机理上研究了 PD 涂层的影响。结果表明，GNRs 的 PD 涂层抑制了不想要的金簇离子的产生，增强了光热转换和 LDI-TOF-MS 的效率，并扩大了工作分子量范围。
