Foulser Peter, Abbasi Yasmin, Mathilakath Anand, Nilforooshan Ramin
Department of Psychiatry, Surrey and Borders Partnership NHS Foundation Trust, Leatherhead, Surrey, UK.
BMJ Case Rep. 2017 Jun 2;2017:bcr-2017-220079. doi: 10.1136/bcr-2017-220079.
We describe the case of a 62-year-old man with a history of bipolar disorder, previously stable on lithium for over 20 years, who presented with a manic relapse and signs of lithium toxicity in the form of a coarse tremor. Serum lithium levels were in the normal range, and the patient had stage 3 chronic kidney disease. He was admitted for treatment under Section 2 of the Mental Health Act, and after stopping lithium was started on olanzapine. Signs of lithium toxicity improved after withdrawal of lithium. This case highlights the need to treat normal serum lithium levels with caution in patients showing signs of clinical lithium toxicity.
我们描述了一名62岁男性的病例,他有双相情感障碍病史,之前服用锂盐超过20年病情稳定,此次出现躁狂复发以及以粗大震颤形式表现的锂中毒迹象。血清锂水平在正常范围内,且该患者患有3期慢性肾脏病。他依据《精神卫生法》第2条入院接受治疗,停用锂盐后开始服用奥氮平。停用锂盐后锂中毒迹象有所改善。该病例凸显了对于出现临床锂中毒迹象的患者,即便血清锂水平正常也需谨慎处理这一必要性。