Department of Medicine, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia
Department of Medicine, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia.
BMJ Case Rep. 2021 Nov 17;14(11):e246499. doi: 10.1136/bcr-2021-246499.
Lithium is a medication with a variety of medical usage for various diseases including bipolar mood disorder. As the therapeutic window of lithium is narrow, its usage is commonly associated with toxicity. Lithium toxicity affects multiple systems especially the central nervous system, leading to neuropsychiatric complications. Haemodialysis is an effective method for lithium removal especially in severe lithium toxicity such as neurotoxicity with electroencephalogram changes. We describe a case of lithium neurotoxicity with electroencephalographic abnormalities which was reversed following haemodialysis.
锂是一种具有多种医学用途的药物,可用于治疗多种疾病,包括双相情感障碍。由于锂的治疗窗狭窄,其使用通常与毒性有关。锂中毒会影响多个系统,特别是中枢神经系统,导致神经精神并发症。血液透析是一种有效的锂清除方法,特别是在严重的锂中毒,如伴有脑电图改变的神经毒性。我们描述了一例锂中毒性脑病,经血液透析后异常脑电图恢复正常。