Richard M L, Liskow B I, Perry P J
J Clin Psychiatry. 1985 Mar;46(3):79-83.
The incidence of CNS stimulant use among 300 patients admitted to an acute care psychiatric facility was estimated to be 31% overall; 11% of patients admitted to use within 6 months of the index hospitalization. A number of previously described relationships between stimulant use and schizophrenia were confirmed. Relapsing schizophrenics utilized stimulants prior to hospitalization more often than nonschizophrenic patients; outpatient antipsychotic prophylaxis did not prevent these relapses. It is concluded that stimulants partially contribute to relapse in schizophrenics.
据估计,在一家急症护理精神病院收治的300名患者中,中枢神经系统兴奋剂的使用总体发生率为31%;11%的患者在首次住院后的6个月内开始使用。兴奋剂使用与精神分裂症之间的一些先前描述的关系得到了证实。复发型精神分裂症患者在住院前比非精神分裂症患者更常使用兴奋剂;门诊抗精神病药物预防并不能防止这些复发。得出的结论是,兴奋剂在一定程度上导致了精神分裂症患者的复发。