Popiela Tadeusz Jan, Brzegowy Paweł, Łasocha Bartłomiej, Urbanik Andrzej
Chair of Radiology, Jagiellonian University Collegium Medicum, Krakow, Poland.
Chair of Radiology, Jagiellonian University Collegium Medicum, Krakow, Poland.
Neurol Neurochir Pol. 2017 Jul-Aug;51(4):304-310. doi: 10.1016/j.pjnns.2017.05.002. Epub 2017 May 18.
The objective of this work is to analyze the effectiveness of Penumbra 400 micro-coils in the embolization of large cerebral aneurysms.
A retrospective analysis has been conducted in a group of 32 patients at the average age of 54.5 years (30-84) for whose embolization the P400 micro-coils (P400) have been used. A control group consisted of 44 patients at the average age of 52.7 years (24-82) in whose aneurysm embolization the 18 micro-coils (MC) have been utilized.
The respective percentages of micro-coil packing density in aneurysm sacs were 31.5% for P400 and 29% for MC. The average P400 fluoroscopy time was 21min, and 34min in case of MC. The average number of used micro-coils was 3.9 for P400 and 5.6 for MC. The radiation dose received by a patient was 1.7Gy/2.2Gy, respectively. The recanalization of P400 has occurred in 14/31 cases (45%), and for MC it has occurred in 23/44 (52%) patients. One patient died due to early recanalization after P400 aneurysm embolization.
Procedures with use of the P400 demonstrate minimally higher effectiveness of large aneurysms embolization in comparison with the MS with a not much shorter duration and reduction of a radiation dose that a patient receives.
本研究旨在分析Penumbra 400微线圈在大型脑动脉瘤栓塞治疗中的有效性。
对平均年龄54.5岁（30 - 84岁）的32例使用P400微线圈（P400）进行栓塞治疗的患者进行回顾性分析。对照组由平均年龄52.7岁（24 - 82岁）的44例使用18微线圈（MC）进行动脉瘤栓塞治疗的患者组成。
动脉瘤囊内微线圈填充密度的百分比分别为：P400为31.5%，MC为29%。P400的平均透视时间为21分钟，MC为34分钟。P400平均使用的微线圈数量为3.9个，MC为5.6个。患者接受的辐射剂量分别为1.7Gy/2.2Gy。P400组有14/31例（45%）发生再通，MC组有23/44例（52%）发生再通。1例患者在P400动脉瘤栓塞术后因早期再通死亡。
与MC相比，使用P400进行的手术在大型动脉瘤栓塞治疗中显示出略高的有效性，且持续时间缩短不多，患者接受的辐射剂量降低。
