Rahimi Asal, Timmerman Robert
Department of Radiation Oncology, University of Texas Southwestern, Dallas, TX.
Department of Radiation Oncology, University of Texas Southwestern, Dallas, TX; Department of Neurosurgery, University of Texas Southwestern, Dallas, TX.
Semin Radiat Oncol. 2017 Jul;27(3):279-288. doi: 10.1016/j.semradonc.2017.02.007. Epub 2017 Feb 20.
Several improvements in breast cancer radiation delivery have been realized using new techniques over the past several decades. As an example, for early stage disease, there has been active investigation of partial breast irradiation (PBI) vs whole breast irradiation. Although still investigational, PBI reduces the treatment volumes, doses to organs at risk, and may improve cosmesis. Over the past 2 decades PBI has been delivered via interstitial brachytherapy, intracavitary brachytherapy, intraoperative radiation therapy, or 3-dimensional external beam radiation therapy. More recently, there has been growing evidence that supports stereotactic body radiation therapy as a safe and effective new treatment for early stage breast cancer. This article describes this new treatment opportunity and reviews the emerging data of stereotactic partial breast irradiation.
在过去几十年中，通过新技术实现了乳腺癌放疗的多项改进。例如，对于早期疾病，一直在积极研究部分乳腺照射（PBI）与全乳照射。尽管仍处于研究阶段，但PBI可减少治疗体积、降低对危及器官的剂量，并可能改善美容效果。在过去20年中，PBI已通过组织间近距离放疗、腔内近距离放疗、术中放疗或三维外照射放疗来实施。最近，越来越多的证据支持立体定向体部放疗作为早期乳腺癌的一种安全有效的新治疗方法。本文介绍了这种新的治疗机会，并综述了立体定向部分乳腺照射的新出现的数据。
