Park Kye-Yeung, Hwang Hwan-Sik, Park Hoon-Ki
Department of Family Medicine, Hanyang University Medical Center, 222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, South Korea.
Arch Osteoporos. 2017 Dec;12(1):56. doi: 10.1007/s11657-017-0349-9. Epub 2017 Jun 4.
The prevention, education, and treatment of osteoporosis are all recognized as important components in men as well as women. This study revealed that the lifestyle factors associated with male osteoporosis included being underweight and being a current smoker. Being overweight or obese and having a regular exercise habit were negatively associated with male osteoporosis.
Osteoporosis is a significant health problem in Korea and worldwide. Although osteoporosis is less prevalent in males than in females, the fracture-related mortality rate is higher in males than in females. The aim of this study was to investigate the relationship of modifiable lifestyle factors in males with osteoporosis.
A case-control study was performed in men who visited a single university hospital for a medical check-up between August 2003 and July 2016. Patients were classified in the case group according to the World Health Organization (WHO) Osteoporosis Criteria. The control group was created by matching patients according to age and check-up date. Lifestyle factors were evaluated by a self-assessment questionnaire. Multivariate conditional logistic regression was used to examine the association between lifestyle factors and male osteoporosis with age stratification at 50 years.
A total of 1304 subjects were included in this analysis, 326 of whom were in the case group and 978 of whom were in the control group. Within their age group, subjects with osteoporosis were more often underweight (odds ratio [OR] = 2.35, 95% confidence interval [CI], 1.11-4.98) or more often current smokers (2.22, 1.50-3.28) than control subjects. The subjects who were overweight (0.45, 0.32-0.64), obese (0.19, 0.13-0.27), had an irregular exercise habit (0.64, 0.43-0.94), or had a regular exercise habit (0.40, 0.28-0.57) were more likely to have normal bone status. Alcohol drinking habit had no significant association with male osteoporosis.
Several modifiable lifestyle factors were associated with male osteoporosis. Current smokers at any age and underweight men below age 50 were more likely to have osteoporosis, whereas men who were overweight, obese, or had a regular exercise habit were more likely to have normal bone status, regardless of age.
骨质疏松症的预防、教育和治疗在男性和女性中均被视为重要组成部分。本研究表明，与男性骨质疏松症相关的生活方式因素包括体重过轻和当前吸烟。超重或肥胖以及有规律的运动习惯与男性骨质疏松症呈负相关。
骨质疏松症在韩国乃至全球都是一个重大的健康问题。尽管男性骨质疏松症的患病率低于女性，但男性骨折相关死亡率高于女性。本研究的目的是调查男性中可改变的生活方式因素与骨质疏松症之间的关系。
对2003年8月至2016年7月期间到一家大学医院进行体检的男性进行病例对照研究。根据世界卫生组织（WHO）骨质疏松症标准将患者分为病例组。通过根据年龄和检查日期匹配患者来创建对照组。生活方式因素通过自我评估问卷进行评估。采用多变量条件逻辑回归分析50岁时按年龄分层的生活方式因素与男性骨质疏松症之间的关联。
本分析共纳入1304名受试者，其中326名在病例组，978名在对照组。在同一年龄组中，骨质疏松症患者比对照组更常体重过轻（比值比[OR]=2.35，95%置信区间[CI]，1.11 - 4.98）或更常为当前吸烟者（2.22，1.50 - 3.28）。超重（0.45，0.32 - 0.64）、肥胖（0.19，0.13 - 0.27）、有不规律运动习惯（0.64，0.43 - 0.94）或有规律运动习惯（0.40，0.28 - 0.57）的受试者更有可能骨骼状况正常。饮酒习惯与男性骨质疏松症无显著关联。
几个可改变的生活方式因素与男性骨质疏松症相关。任何年龄的当前吸烟者以及50岁以下体重过轻的男性患骨质疏松症的可能性更大，而超重、肥胖或有规律运动习惯的男性无论年龄大小，骨骼状况正常的可能性更大。
