Shadfan Adam, Pawlowski Michal, Wang Ye, Subramanian Kaushik, Gabay Ilan, Ben-Yakar Adela, Tkaczyk Tomasz
Rice University, Tkaczyk Group, Department of Bioengineering, 6100 Main Street, Houston, Texas 77005, United States.
University of Texas at Austin, Ben-Yakar Group, Mechanical Engineering Department, 1 University Station C2200, Austin, Texas 78712, United States.
Opt Eng. 2016 Feb;55(2). doi: 10.1117/1.OE.55.2.025107. Epub 2016 Feb 23.
A miniature laser ablation probe relying on an optical fiber to deliver light requires a high coupling efficiency objective with sufficient magnification in order to provide adequate power and field for surgery. A diffraction-limited optical design is presented that utilizes high refractive index zinc sulfide to meet specifications while reducing the miniature objective down to two lenses. The design has a hypercentric conjugate plane on the fiber side and is telecentric on the tissue end. Two versions of the objective were built on a diamond lathe-a traditional cylindrical design and a custom-tapered mount. Both received an antireflective coating. The objectives performed as designed in terms of observable resolution and field of view as measured by imaging a 1951 USAF resolution target. The slanted edge technique was used to find Strehl ratios of 0.75 and 0.78, respectively, indicating nearly diffraction-limited performance. Finally, preliminary ablation experiments indicated threshold fluence of gold film was comparable to similar reported probes.
一种依靠光纤传输光的微型激光消融探针需要一个具有足够放大倍数的高耦合效率物镜,以便为手术提供足够的功率和视野。本文提出了一种衍射极限光学设计,该设计利用高折射率硫化锌来满足规格要求,同时将微型物镜减少到两个透镜。该设计在光纤侧具有超同心共轭平面,在组织端是远心的。物镜的两个版本是在金刚石车床上制造的——传统的圆柱形设计和定制的锥形安装。两者都接受了抗反射涂层。通过对1951年美国空军分辨率靶标成像测量,物镜在可观察分辨率和视野方面的表现符合设计要求。采用倾斜边缘技术分别得到了0.75和0.78的斯特列尔比,表明其性能接近衍射极限。最后,初步消融实验表明金膜的阈值通量与报道的类似探针相当。