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经皮胆囊造瘘术及水分离技术在靠近胆囊的肝包膜下平滑肌肉瘤转移灶射频消融中的保护作用

Percutaneous Cholecystostomy and Hydrodissection in Radiofrequency Ablation of Liver Subcapsular Leiomyosarcoma Metastasis Adjacent to the Gallbladder: Protective Effect.

作者信息

Azevedo André, Falsarella Priscila, Rocha Rafael, Rahal Antônio, Garcia Rodrigo

机构信息

Department of Interventional Radiology, Hospital Israelita Albert Einstein, São Paulo, Brazil.

出版信息

J Radiol Case Rep. 2016 Oct 31;10(10):24-32. doi: 10.3941/jrcr.v10i10.2677. eCollection 2016 Oct.

Abstract

Uterine leiomyosarcoma is an uncommon pathology, predominantly found in aged population. Patients with metastatic disease have poor survival and therapy mainly consists of palliative systemic chemotherapy. However, more aggressive strategies such as radiofrequency ablation (RFA) may benefit patients with limited secondary disease. RFA is considered a simple and safe modality for treatment of hepatic lesions. The benefits related to RFA include low morbidity, short hospital stay and the possibility to repeat the procedure when necessary due to recurrences. However, minor and major complications related to mechanical and thermal damage may occur, especially in cases of tumors adjacent to extrahepatic organs and those at subcapsular position. This case report shows a successful RFA of two hepatic subcapsular leiomyosarcoma metastases neighbouring the gallbladder, without a safe cleavage plane from it. Combined hydrodissection, percutaneous cholecystostomy and continuous irrigation were performed as effective techniques to prevent thermal injury. Clinical and radiological follow up demonstrates no local complication.

摘要

子宫平滑肌肉瘤是一种罕见的病理类型,主要见于老年人群。转移性疾病患者的生存率较低,治疗主要包括姑息性全身化疗。然而,诸如射频消融(RFA)等更积极的策略可能使继发性疾病有限的患者受益。RFA被认为是一种治疗肝脏病变的简单且安全的方式。与RFA相关的益处包括发病率低、住院时间短以及因复发而在必要时可重复进行该操作的可能性。然而,可能会发生与机械性和热损伤相关的轻微和严重并发症,尤其是在肿瘤邻近肝外器官以及位于包膜下位置的情况下。本病例报告展示了对两个邻近胆囊的肝脏包膜下平滑肌肉瘤转移灶成功进行RFA,且与胆囊之间没有安全的分离平面。联合水分离、经皮胆囊造瘘术和持续冲洗作为预防热损伤的有效技术。临床和影像学随访显示无局部并发症。

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