Huh Hyub, Jung Jae Seung, Park Sang Jae, Park Min Kyung, Lim Choon Hak, Yoon Seung Zhoo
Department of Anesthesiology and Pain Medicine, Korea University College of Medicine, Seoul, Korea.
Department of Thoracic and Cardiovascular Surgery, Korea University College of Medicine, Seoul, Korea.
Korean J Anesthesiol. 2017 Jun;70(3):345-349. doi: 10.4097/kjae.2017.70.3.345. Epub 2017 Feb 3.
Malignant hyperthermia (MH) may lead to metabolic crisis of skeletal muscle in susceptible individuals following exposure to triggering agents such as volatile anesthetics or depolarizing muscle relaxants. MH is a rare and a potentially lethal disease, which can lead to cardiac arrest. We report a case of severe MH, in which the rapidly evolving signs of hypermetabolism eventually resulted in cardiac arrest. Despite conventional treatments following cardiopulmonary resuscitation, the patient's vital signs did not improve. Therefore, we applied extracorporeal membrane oxygenation for providing hemodynamic support.
恶性高热（MH）可能会导致易感个体在接触触发剂（如挥发性麻醉剂或去极化肌肉松弛剂）后出现骨骼肌代谢危机。MH是一种罕见且可能致命的疾病，可导致心脏骤停。我们报告一例严重的MH病例，其中快速进展的高代谢体征最终导致心脏骤停。尽管在心肺复苏后进行了常规治疗，但患者的生命体征并未改善。因此，我们应用体外膜肺氧合来提供血流动力学支持。
