Kim Hyae-Jin, Lee Hyeon Jeong, Lee Do Won, Kim Jae Yeon, Kwon Jae Young, Kim Hae-Kyu, Kim Won-Sung, Hwang Boo-Young
Department of Anesthesia and Pain Medicine, Pusan National University School of Medicine, Busan, Korea.
Korean J Anesthesiol. 2017 Jun;70(3):356-360. doi: 10.4097/kjae.2017.70.3.356. Epub 2017 Feb 3.
Anesthetic experience in frontotemporal dementia (FTD) with severe hypotension associated autonomic dysfunction has not yet been reported. Here in case, we report on the case of treatment with vasopressin to refractory hypotension in FTD patient. A 54-year-old male presented with a ten-year history of FTD with frequent syncope. The patient was scheduled to undergo subtotal gastrectomy for resection of stomach cancer. During the operation, sudden hypotension occurred and it was refractory to fluid and 1 unit of blood resuscitation and did not respond to catecholamine. Transesophageal echocardiography showed normal heart with adequate volume state. After intravenous administration of arginine vasopressin, the patient's vital signs returned to baseline values. Arginine vasopressin might be considered as a valuable alternative for treatment of severe refractory hypotension in autonomic dysfunction patients with FTD.
额颞叶痴呆(FTD)合并严重低血压相关自主神经功能障碍的麻醉经验尚未见报道。在此,我们报告1例使用血管加压素治疗FTD患者顽固性低血压的病例。一名54岁男性,有10年FTD病史,频繁晕厥。该患者计划接受胃癌切除术的胃大部切除术。手术过程中,突然发生低血压,对液体复苏和1单位输血无反应,对儿茶酚胺也无反应。经食管超声心动图显示心脏正常,容量状态合适。静脉注射精氨酸血管加压素后,患者生命体征恢复至基线值。精氨酸血管加压素可被视为治疗FTD自主神经功能障碍患者严重顽固性低血压的一种有价值的替代方法。