机会致病菌还是无辜旁观者？一例半乳甘露聚糖交叉反应的病例分析及演示
: Opportunistic pathogen or idle bystander? A case analysis with demonstration of galactomannan cross-reactivity.
作者信息
Hesse Shayla E, Luethy Paul M, Beigel John H, Zelazny Adrian M
机构信息
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA.
出版信息
Med Mycol Case Rep. 2017 May 22;17:8-10. doi: 10.1016/j.mmcr.2017.05.003. eCollection 2017 Sep.
We present a case of an immunocompromised woman with fever, pulmonary infiltrates and multiple bronchoalveolar lavage (BAL) cultures positive for with a concomitant high BAL galactomannan level. We report the results of galactomannan testing performed on culture supernatants from her strain that confirmed the suspected cross-reactivity. Finally, we discuss the clinical significance and antifungal susceptibility of in our case and review the literature.
我们报告一例免疫功能低下的女性患者，其有发热、肺部浸润，多次支气管肺泡灌洗（BAL）培养对[具体真菌名称未给出]呈阳性，同时BAL半乳甘露聚糖水平升高。我们报告了对其[具体真菌名称未给出]菌株培养上清液进行半乳甘露聚糖检测的结果，证实了疑似交叉反应。最后，我们讨论了本例中[具体真菌名称未给出]的临床意义和抗真菌药敏情况，并复习了相关文献。
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