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脂质体两性霉素B、泊沙康唑和口服两性霉素B联合治疗免疫功能低下患者的胃肠道疾病

Combination liposomal amphotericin B, posaconazole and oral amphotericin B for treatment of gastrointestinal in an immunocompromised patient.

作者信息

Anderson Anthony, McManus Dayna, Perreault Sarah, Lo Ying-Chun, Seropian Stuart, Topal Jeffrey E

机构信息

Department of Pharmacy, Yale New Haven Hospital, 20 York Street, New Haven, CT 06510, USA.

Department of Pathology, Yale School of Medicine, 20 York Street, New Haven, CT 06510, USA.

出版信息

Med Mycol Case Rep. 2017 May 24;17:11-13. doi: 10.1016/j.mmcr.2017.05.004. eCollection 2017 Sep.

Abstract

Mucormycosis is a life threatening infection caused by fungi in the order Mucorales. Mucormycosis can affect any organ system with rhino-orbital-cerebral and pulmonary infections being the most predominant infection types. Gastrointestinal mucormycosis is rare and accounts for only 4-7% of all cases. Here, we present a case of invasive gastrointestinal mucormycosis in an immunocompromised host treated with systemic and topical anti-mold therapy.

摘要

毛霉病是一种由毛霉目真菌引起的危及生命的感染。毛霉病可累及任何器官系统,其中鼻眶脑型和肺型感染是最主要的感染类型。胃肠道毛霉病较为罕见,仅占所有病例的4-7%。在此,我们报告一例免疫功能低下宿主发生的侵袭性胃肠道毛霉病病例,该病例接受了全身及局部抗霉菌治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ef0/5447657/8291e45195a0/gr1.jpg

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