柳氮磺胺吡啶：一种用于长期控制类风湿性关节炎的安全、有效药物。与金硫代苹果酸钠的比较。
Sulphasalazine: a safe, effective agent for prolonged control of rheumatoid arthritis. A comparison with sodium aurothiomalate.
作者信息
Bax D E, Amos R S
出版信息
Ann Rheum Dis. 1985 Mar;44(3):194-8. doi: 10.1136/ard.44.3.194.
Abstract
The place of sulphasalazine in the management of rheumatoid arthritis over prolonged periods of time has been compared and contrasted with that of sodium aurothiomalate. One hundred and forty-three patients (59 on sulphasalazine, 84 on sodium aurothiomalate) have been treated for periods of up to 42 months. Sulphasalazine is highly effective for some patients, though probably less frequently than sodium aurothiomalate. However, its safety profile is far superior, and very long-term treatment with sulphasalazine is a safe option for treatment of rheumatoid arthritis.
摘要
已对柳氮磺胺吡啶和金硫代苹果酸钠在长时间治疗类风湿性关节炎方面的作用进行了比较和对比。143名患者（59名使用柳氮磺胺吡啶，84名使用金硫代苹果酸钠）接受了长达42个月的治疗。柳氮磺胺吡啶对一些患者非常有效，尽管可能不如金硫代苹果酸钠频繁。然而，其安全性要高得多，长期使用柳氮磺胺吡啶治疗类风湿性关节炎是一种安全的选择。
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