Long-term Clinical Outcomes of Kidney Re-transplantation.
作者信息
Yeo S M, Kim Y, Kang S S, Park W Y, Jin K, Park S B, Park U J, Kim H T, Cho W H, Han S
机构信息
Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea.
Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea; Keimyung University Kidney Institute, Daegu, Republic of Korea.
出版信息
Transplant Proc. 2017 Jun;49(5):997-1000. doi: 10.1016/j.transproceed.2017.03.057.
BACKGROUND
Kidney re-transplantation is commonly considered to have a higher immunological risk than first kidney transplantation. Because of the organ shortage and increasing waiting lists, long-term outcomes of kidney re-transplantation are being studied. However, reports of re-transplantation outcomes are not common. We have reported our 30 years of experience with second kidney transplantations.
METHODS
Of 1210 kidney transplantations between November 1982 and August 2016 performed in our hospital, 105 were second kidney transplantations (2nd KT). Living donor KT was 44; deceased donor KT was 61.
RESULTS
Patient survival rates at 1, 5, and 10 years were 100%, 97.2%, and 90.7%, and graft survival rates were 97.0%, 94.6%, and 71.5%, respectively. The leading cause of graft failure in the 2nd KT was chronic rejection (60%). In addition, induction immunosuppressant, maintenance immunosuppressant, delayed graft function, and graft survival time at the 1st KT had a significant impact on graft survival time at the 2nd KT.
CONCLUSIONS
Reasonable results in both patient survival and graft survival rates were found in the 2nd KT. Careful monitoring of immunologic risk is needed.
Zotero 插件