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Stability of acyl glucuronides in blood, plasma, and urine: studies with zomepirac.

作者信息

Smith P C, Hasegawa J, Langendijk P N, Benet L Z

出版信息

Drug Metab Dispos. 1985 Jan-Feb;13(1):110-2.

PMID:2858367
Abstract
摘要

相似文献

1
Stability of acyl glucuronides in blood, plasma, and urine: studies with zomepirac.
Drug Metab Dispos. 1985 Jan-Feb;13(1):110-2.
2
High-performance liquid chromatographic determination of tolmetin, tolmetin glucuronide and its isomeric conjugates in plasma and urine.高效液相色谱法测定血浆和尿液中的托美丁、托美丁葡萄糖醛酸苷及其异构体结合物。
J Chromatogr. 1987 Sep 25;420(2):349-56. doi: 10.1016/0378-4347(87)80190-1.
3
Renal handling of zomepirac sodium (McN-2783-21-98) in the rat.大鼠对佐美酸（McN - 2783 - 21 - 98）的肾脏处理情况。
J Pharmacol Exp Ther. 1979 Jun;209(3):366-70.
4
Continuous body fluid monitoring for zomepirac by fully automated high-performance liquid chromatography.采用全自动高效液相色谱法对佐美酸进行连续体液监测。
Arzneimittelforschung. 1985;35(1):152-4.
5
Effect of probenecid on the formation and elimination of acyl glucuronides: studies with zomepirac.丙磺舒对酰基葡萄糖醛酸苷形成和消除的影响：以佐美酸进行的研究
Clin Pharmacol Ther. 1985 Aug;38(2):121-7. doi: 10.1038/clpt.1985.146.
6
Apparent intramolecular acyl migration of zomepirac glucuronide.佐美酸葡糖醛酸的明显分子内酰基迁移。
Drug Metab Dispos. 1982 Sep-Oct;10(5):469-73.
7
Simultaneous determination of zomepirac and its major metabolite zomepirac glucuronide in human plasma and urine.同时测定人血浆和尿液中佐美酸及其主要代谢物佐美酸葡糖醛酸苷。
J Chromatogr. 1984 May 11;307(2):371-9. doi: 10.1016/s0378-4347(00)84108-0.
8
Voltammetric studies of zomepirac sodium and its determination in tablets by differential-pulse polarography.佐美酸纳的伏安法研究及其片剂的差示脉冲极谱法测定
Analyst. 1983 Aug;108(1289):997-1002. doi: 10.1039/an9830800997.
9
Dose-dependent pharmacokinetics and renal handling of zomepirac in rhesus monkeys.猴体内佐美酸的剂量依赖性药代动力学及肾脏处理情况
J Pharmacol Exp Ther. 1981 Dec;219(3):665-8.
10
Simultaneous determination of tolmetin and its metabolite in biological fluids by high-performance liquid chromatography.高效液相色谱法同时测定生物流体中托美汀及其代谢物
J Chromatogr. 1982 Oct 8;232(1):119-28. doi: 10.1016/s0378-4347(00)86014-4.

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Safety and pharmacokinetics of Bevirimat (PA-457), a novel inhibitor of human immunodeficiency virus maturation, in healthy volunteers.新型人类免疫缺陷病毒成熟抑制剂贝维拉马（PA - 457）在健康志愿者中的安全性和药代动力学
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The in vitro biosynthesis and stability measurement with agyl-glycuronide isoformes of the main metabolite of ipriflavone.淫羊藿苷元主要代谢产物的酰基葡萄糖醛酸异构体的体外生物合成及稳定性测定
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Direct gradient reversed-phase HPLC analysis and preliminary pharmacokinetics of nalidixic acid, 7-hydroxymethylnalidixic acid, 7-carboxynalidixic acid, and their corresponding glucuronide conjugates in humans.
萘啶酸、7-羟甲基萘啶酸、7-羧基萘啶酸及其相应葡萄糖醛酸缀合物在人体内的直接梯度反相高效液相色谱分析及初步药代动力学研究
Pharm World Sci. 1993 Jun 18;15(3):98-104. doi: 10.1007/BF02113937.
4
Reversible binding of tolmetin, zomepirac, and their glucuronide conjugates to human serum albumin and plasma.托美丁、佐美酸及其葡萄糖醛酸共轭物与人血清白蛋白和血浆的可逆结合。
J Pharmacokinet Biopharm. 1994 Feb;22(1):19-40. doi: 10.1007/BF02353408.
5
Difloxacin metabolism and pharmacokinetics in humans after single oral doses.单次口服剂量后地氟沙星在人体内的代谢及药代动力学
Antimicrob Agents Chemother. 1986 Nov;30(5):689-93. doi: 10.1128/AAC.30.5.689.
6
Pharmacokinetics of nalidixic acid in man: hydroxylation and glucuronidation.
Pharm Weekbl Sci. 1988 Oct 14;10(5):193-9. doi: 10.1007/BF01956870.
7
Procedures to characterize in vivo and in vitro enantioselective glucuronidation properly: studies with benoxaprofen glucuronides.正确表征体内和体外对映体选择性葡萄糖醛酸化的方法：对苯恶洛芬葡萄糖醛酸苷的研究
Pharm Res. 1989 Feb;6(2):125-32. doi: 10.1023/a:1015976425031.
8
Irreversible binding of tolmetin glucuronic acid esters to albumin in vitro.托美丁葡萄糖醛酸酯在体外与白蛋白的不可逆结合。
Pharm Res. 1990 Jan;7(1):21-7. doi: 10.1023/a:1015823206607.
9
Direct measurement of probenecid and its glucuronide conjugate by means of high pressure liquid chromatography in plasma and urine of humans.通过高压液相色谱法直接测定人体血浆和尿液中丙磺舒及其葡糖醛酸共轭物。
Pharm Weekbl Sci. 1992 Jun 19;14(3):83-7. doi: 10.1007/BF01962691.
10
Capacity-limited renal glucuronidation of probenecid by humans. A pilot Vmax-finding study.人体对丙磺舒的肾葡萄糖醛酸化能力受限。一项初步的最大反应速度（Vmax）探索性研究。
Pharm Weekbl Sci. 1992 Oct 16;14(5):325-31. doi: 10.1007/BF01977622.