Macedo Filipa, Ladeira Katia, Pinho Filipa, Saraiva Nadine, Bonito Nuno, Pinto Luisa, Goncalves Francisco
Medical Oncology Department, Portuguese Oncology Institute, Coimbra, Portugal.
Internal Medicine Department, Braga Hospital, Braga, Portugal.
Oncol Rev. 2017 May 9;11(1):321. doi: 10.4081/oncol.2017.321. eCollection 2017 Mar 3.
Bone is a frequent site of metastases and typically indicates a short-term prognosis in cancer patients. Once cancer has spread to the bones it can rarely be cured, but often it can still be treated to slow its growth. The majority of skeletal metastases are due to breast and prostate cancer. Bone metastasis is actually much more common than primary bone cancers, especially in adults. The diagnosis is based on signs, symptoms and imaging. New classes of drugs and new interventions are given a better quality of life to these patients and improved the expectancy of life. It is necessary a multidisciplinary approach to treat patients with bone metastasis. In this paper we review the types, clinical approach and treatment of bone metastases.
骨骼是转移瘤的常见部位，通常预示着癌症患者的短期预后。一旦癌症扩散至骨骼，很少能够治愈，但通常仍可进行治疗以减缓其生长。大多数骨转移瘤源于乳腺癌和前列腺癌。骨转移瘤实际上比原发性骨癌更为常见，尤其是在成年人中。诊断基于体征、症状和影像学检查。新型药物和新的干预措施提高了这些患者的生活质量，并延长了预期寿命。治疗骨转移瘤患者需要多学科方法。在本文中，我们综述了骨转移瘤的类型、临床方法和治疗。
