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腹腔镜肾上腺切除术在肾上腺肿瘤治疗中的应用——单中心经验

The usefulness of laparoscopic adrenalectomy in the treatment of adrenal neoplasms - a single-centre experience.

作者信息

Pogorzelski Ryszard, Toutounchi Sadegh, Krajewska Ewa, Fiszer Patryk, Kącka Agata, Piotrowski Mariusz, Szostek Małgorzata, Wołoszko Tomasz, Celejewski Krzysztof, Ambroziak Urszula, Bednarczuk Tomasz, Gałązka Zbigniew

机构信息

Department of General and Endocrine Surgery, Medical University of Warsaw, Poland.

出版信息

Endokrynol Pol. 2017;68(4):407-410. doi: 10.5603/EP.a2017.0033. Epub 2017 Jun 6.

Abstract

INTRODUCTION

Adrenal neoplasms comprise about 10% of all tumours affecting this organ and constitute a significant, at first diagnostic and subsequently therapeutic, problem, especially since a relatively high proportion of neoplastic lesions are asymptomatic. The number of diagnosed metastases to adrenal glands is increasing. Surgical treatment involves both open surgery as well as laparoscopy.

MATERIAL AND METHODS

There were 245 adrenalectomies performed at our centre due to various indications over the past four years. In 27 (11.5%) cases neoplasms were diagnosed in the final histopahtological examination. In 11 (40.7%) cases primary adrenal cortex tumours were diagnosed, metastases from other solid organ tumours were identified in another 12 (44.4%) patients, and rarer neoplasms were diagnosed in the remaning 4 (14.8%) subjects. Cases of malignant pheochromocytoma were not included in this report.

RESULTS

Laparoscopic adrenalectomy was performed in 23 (85.2%) subjects, while the ramaining 4 (12.9%) patients were subject to open adrenalectomy (conversion to open procedure in one case). There were no deaths or significant complications in the perioperative period. Comparing mean duration of open (140 minutes) and laparoscopic (190 minutes) procedures yielded a statistically significant difference (p = 0.02). There was no statistically significant difference found in the duration of operation with regard to laparoscopic adrenalectomies of tumours less than 50 mm and over 55 mm in diameter (p = 0.16).

CONCLUSIONS

Laparoscopic adrenalectomy is a safe and effective method of treatment of adrenal tumours. Its oncological completeness is comparable (to open surgery) when performed by experienced surgical teams. Laparoscopy is the reason for the smooth postoperative course observed in most patients.

摘要

引言

肾上腺肿瘤约占累及该器官所有肿瘤的10%,构成了一个重大问题,首先是诊断问题,其次是治疗问题,尤其是因为相当一部分肿瘤性病变是无症状的。诊断为肾上腺转移瘤的病例数量正在增加。手术治疗包括开放手术和腹腔镜手术。

材料与方法

在过去四年中,我们中心因各种适应症进行了245例肾上腺切除术。在27例(11.5%)病例中,最终组织病理学检查诊断为肿瘤。在11例(40.7%)病例中诊断为原发性肾上腺皮质肿瘤,另外12例(44.4%)患者发现是其他实体器官肿瘤的转移灶,其余4例(14.8%)诊断为罕见肿瘤。本报告未包括恶性嗜铬细胞瘤病例。

结果

23例(85.2%)患者接受了腹腔镜肾上腺切除术,其余4例(12.9%)患者接受了开放肾上腺切除术(其中1例转为开放手术)。围手术期无死亡或严重并发症。比较开放手术(140分钟)和腹腔镜手术(190分钟)的平均时长,差异具有统计学意义(p = 0.02)。对于直径小于50mm和大于55mm的肿瘤,腹腔镜肾上腺切除术的手术时长在统计学上无显著差异(p = 0.16)。

结论

腹腔镜肾上腺切除术是治疗肾上腺肿瘤的一种安全有效的方法。由经验丰富的手术团队进行时,其肿瘤切除完整性与开放手术相当。腹腔镜手术是大多数患者术后恢复顺利的原因。

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