Watt A H
Lancet. 1985 Apr 6;1(8432):786-8. doi: 10.1016/s0140-6736(85)91449-7.
It is suggested that adenosine is a mediator of the paroxysmal bradycardias and tachycardias characterising the sick sinus syndrome. Increased sensitivity to adenosine could account for the arrhythmias, which might therefore be suppressed by an adenosine antagonist such as theophylline.
有人提出,腺苷是病态窦房结综合征所特有的阵发性心动过缓和心动过速的介质。对腺苷敏感性增加可能是导致心律失常的原因,因此心律失常可能会被诸如茶碱这类腺苷拮抗剂所抑制。