月桂：精油成分及其生物活性。
Laurus nobilis: Composition of Essential Oil and Its Biological Activities.
作者信息
Caputo Lucia, Nazzaro Filomena, Souza Lucéia Fatima, Aliberti Luigi, De Martino Laura, Fratianni Florinda, Coppola Raffaele, De Feo Vincenzo
机构信息
Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (Salerno), Italy.
Istituto di Scienze dell'Alimentazione, Consiglio Nazionale delle Ricerche (ISA-CNR), Via Roma 64, 83100 Avellino, Italy.
出版信息
Molecules. 2017 Jun 3;22(6):930. doi: 10.3390/molecules22060930.
is native to the southern Mediterranean region and cultivated mainly in Europe and the USA as an ornamental and medicinal plant. The chemical composition of the essential oil (EO) from leaves of collected in Southern Italy, was studied by GC and GC-MS. In all, 55 compounds were identified, accounting for 91.6% of the total oil. 1,8-Cineole (31.9%), sabinene (12.2%), and linalool (10.2%) were the main components. Antimicrobial and antifungal activities of EO and 1,8-cineole were determined in vitro. The cytotoxicity of the EO was evaluated against SH-SY5Y cell line, as well as the influence of the EO on the expression of adenylate cyclase 1 (ADCY1), suggesting possible oil effects on the Central Nervous System.
原产于地中海地区南部，主要在欧洲和美国作为观赏植物和药用植物进行种植。通过气相色谱（GC）和气相色谱-质谱联用（GC-MS）对采自意大利南部的[植物名称]叶片精油（EO）的化学成分进行了研究。共鉴定出55种化合物，占总油含量的91.6%。1,8-桉叶素（31.9%）、桧烯（12.2%）和芳樟醇（10.2%）是主要成分。对EO和1,8-桉叶素的抗菌和抗真菌活性进行了体外测定。评估了EO对SH-SY5Y细胞系的细胞毒性，以及EO对腺苷酸环化酶1（ADCY1）表达的影响，提示该精油可能对中枢神经系统有作用。
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