Wu Fanglan, Chen Yicun, Gao Ming, Li Wei, Zhao Yunxiao, Wang Yangdong
State Key Laboratory of Tree Genetics and Breeding, Chinese Academy of Forestry, Beijing 100091, China.
College of Forest, Nanjing Forestry University, Nanjing 210037, China.
Int J Mol Sci. 2025 Jun 13;26(12):5690. doi: 10.3390/ijms26125690.
Globally, plant-derived natural products such as essential oils serve as primary sources of functional substances for spices, pharmaceuticals, and other applications. With the increasing focus on health and well-being, alongside ongoing public health challenges, there is a critical need to enhance the deep utilization of natural plant products. Lauraceae family essential oils, characterized by their aromatic, volatile properties and notable biological activities (e.g., antibacterial, antioxidant, insect-repellent), hold significant application value across fragrance, cosmetics, chemical industries, biological pesticides, and medicine. Integrating multi-disciplinary data from biology, genomics, metabolomics, and related fields can accelerate comprehensive insights into the biosynthesis mechanisms and functional roles of these essential oils, thereby promoting the development and application of Lauraceae natural products. This review systematically summarizes the accumulation patterns and compositional characteristics of essential oils across diverse genera of Lauraceae. It further explores the evolutionary dynamics of terpene synthase (TPS) gene families and key genes involved in terpenoid biosynthesis pathways, leveraging genomic datasets from Lauraceae species. Finally, the review highlights future research trends for optimizing Lauraceae essential oil resource utilization and advancing molecular breeding of high-oil-content species within the family.
在全球范围内,植物源天然产物如香精油是香料、药品及其他应用中功能物质的主要来源。随着人们对健康和幸福的关注度不断提高,以及公共卫生挑战持续存在,迫切需要加强对天然植物产品的深度利用。樟科植物精油具有芳香、挥发性特性以及显著的生物活性(如抗菌、抗氧化、驱虫),在香料、化妆品、化工行业、生物农药和医药等领域具有重要的应用价值。整合来自生物学、基因组学、代谢组学及相关领域的多学科数据,能够加速对这些精油生物合成机制和功能作用的全面了解,从而推动樟科天然产物的开发与应用。本综述系统地总结了樟科不同属植物精油的积累模式和成分特征。利用樟科物种的基因组数据集,进一步探讨了萜类合酶(TPS)基因家族的进化动态以及萜类生物合成途径中的关键基因。最后,本综述强调了未来优化樟科精油资源利用和推进该科高含油量物种分子育种的研究趋势。