Tomizawa Minoru, Shinozaki Fuminobu, Hasegawa Rumiko, Shirai Yoshinori, Motoyoshi Yasufumi, Sugiyama Takao, Yamamoto Shigenori, Ishige Naoki
Department of Gastroenterology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Chiba 284-0003, Japan.
Department of Radiology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Chiba 284-0003, Japan.
Exp Ther Med. 2017 Jun;13(6):3497-3502. doi: 10.3892/etm.2017.4401. Epub 2017 Apr 28.
To improve the management of patients with acute cholangitis, the present study compared laboratory test variables between acute cholangitis patients with or without common bile duct (CBD) dilatation [CBDdil(+) and CBDdil(-), respectively]. The medical records of patients diagnosed with acute cholangitis and subjected to endoscopic retrograde cholangiopancreatography between February 2008 and May 2015 were retrospectively analyzed. The present study consisted of 40 men (aged 69.4±8.8 years) and 37 women (aged 68.8±11.6 years). It was observed that CBDdil(-) patients were slightly younger than CBDdil(+) patients (P=0.0976), and levels of C-reactive protein (CRP) were significantly higher in CBDdil(-) patients than in CBDdil(+) patients (P=0.0392). In addition, logistic regression analysis indicated that CRP levels were associated with the presence of CBD dilatation (P=0.0392). These data indicate that patients with acute cholangitis without CBD dilatation tend to be younger and have higher levels of CRP. Thus, in acute cholangitis patients without CBD dilatation, diagnosis should be determined using clinical symptoms and laboratory data.
为改善急性胆管炎患者的管理，本研究比较了伴有或不伴有胆总管（CBD）扩张的急性胆管炎患者（分别为CBD扩张阳性和阴性）之间的实验室检查变量。对2008年2月至2015年5月期间诊断为急性胆管炎并接受内镜逆行胰胆管造影术的患者的病历进行了回顾性分析。本研究包括40名男性（年龄69.4±8.8岁）和37名女性（年龄68.8±11.6岁）。观察到CBD扩张阴性患者比CBD扩张阳性患者略年轻（P = 0.0976），CBD扩张阴性患者的C反应蛋白（CRP）水平显著高于CBD扩张阳性患者（P = 0.0392）。此外，逻辑回归分析表明CRP水平与CBD扩张的存在相关（P = 0.0392）。这些数据表明，无CBD扩张的急性胆管炎患者往往更年轻且CRP水平更高。因此，在无CBD扩张的急性胆管炎患者中，应使用临床症状和实验室数据进行诊断。
