Mirsalehi Marjan, Mohebbi Saleh, Ghajarzadeh Mahsa, Lenarz Thomas, Majdani Omid
Department of Otolaryngology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Imam Khomeyni Hospital Complex, Keshavarz Blvd., Tehran, Iran.
Eur Arch Otorhinolaryngol. 2017 Aug;274(8):3049-3056. doi: 10.1007/s00405-017-4628-2. Epub 2017 Jun 6.
This study was conducted to evaluate the effect of the round window membrane accessibility on the residual hearing after cochlear implantation surgery in adults. Moreover, the effects of the other demographics and intra-operative factors on the residual hearing loss have been evaluated. The hearing preservation cochlear implantation surgery was performed on 64 adults with residual hearing thresholds ≤80 dB at 250 and 500 Hz, who had referred to our tertiary academic center. All the patients underwent a standardized surgical approach with the same straight electrode inserted through the round window membrane. The hearing thresholds at 250, 500, and 1000 Hz were compared in pre-operative and 1 month postoperative pure-tone audiograms. The average hearing threshold shifts at these frequencies was used to evaluate the hearing preservation. The effects of the round window accessibility and other factors (including gender, age, side of the surgery, necessity of anterior-inferior drilling of the round window margin and average insertion speed) on hearing threshold shifts were analyzed. The mean low-frequency hearing threshold shift was found to be 17.5 dB for all the patients. The hearing preservation goal (threshold shifts ≤30 dB) was achieved in 58 patients. Among the evaluated parameters, only accessibility of the round window membrane could change the hearing threshold shifts significantly (p = 0.026), and was a predictor for the hearing loss (B coefficient = 7.5, p = 0.006). Incomplete accessibility of the round window membrane may be a predictor for increased hearing threshold shifts in short-term evaluations after cochlear implantation.
本研究旨在评估圆窗膜的可及性对成人人工耳蜗植入术后残余听力的影响。此外,还评估了其他人口统计学因素和术中因素对残余听力损失的影响。对64例转诊至我们三级学术中心、250和500Hz残余听力阈值≤80dB的成人进行了听力保留人工耳蜗植入手术。所有患者均采用标准化手术方法,通过圆窗膜插入相同的直电极。比较术前和术后1个月纯音听力图中250、500和1000Hz的听力阈值。这些频率下的平均听力阈值变化用于评估听力保留情况。分析了圆窗可及性和其他因素(包括性别、年龄、手术侧、圆窗边缘前下钻孔的必要性和平均插入速度)对听力阈值变化的影响。所有患者的平均低频听力阈值变化为17.5dB。58例患者实现了听力保留目标(阈值变化≤30dB)。在评估的参数中,只有圆窗膜的可及性能显著改变听力阈值变化(p = 0.026),并且是听力损失的一个预测指标(B系数 = 7.5,p = 0.006)。圆窗膜可及性不完全可能是人工耳蜗植入术后短期评估中听力阈值变化增加的一个预测指标。