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[使用Nucleus CI532纤细螺旋电极阵列保留残余听力的可能性。病例报告]

[Possibilities for residual hearing preservation with Nucleus CI532 Slim Modiolar electrode array. Case report].

作者信息

Nagy Roland, Jarabin János András, Dimák Balázs, Perényi Ádám, Tóth Ferenc, Szűts Viktória, Jóri József, Kiss József Géza, Rovó László

机构信息

Általános Orvostudományi Kar, Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Szegedi Tudományegyetem Szeged, Tisza Lajos krt. 111., 6725.

Mérnöki Kar, Élelmiszermérnöki Intézet, Szegedi Tudományegyetem Szeged.

出版信息

Orv Hetil. 2018 Oct;159(41):1680-1688. doi: 10.1556/650.2018.31113.

DOI:10.1556/650.2018.31113
PMID:30295044
Abstract

During the rehabilitation of hearing-impaired patients, the preservation of residual acoustic hearing following cochlear implantation by minimizing the implantation trauma allows for improved hearing performance. To achieve this, minimally invasive, soft surgery methods and thinner, atraumatic electrodes were required. In our present study, we reported a case where Cochlear® Nucleus CI532 Slim Modiolar electrode was implanted in a patient with residual hearing. Our aim was to study the possible preservation of postoperative acoustic residual hearing by audiological monitoring. Since childhood, due to her congenital hearing loss, she has been wearing a conventional, airborne hearing correction device on both ears. Six months before cochlear implantation, we measured the progression on both sides of the hearing loss, so we decided to perform cochlear implantation. The patient had residual hearing on both ears prior to surgery thus the Cochlear® Nucleus CI532 Slim Modiolar Implant was used. The minimally invasive surgery was performed on the patient's right ear through the round window approach. Compared to the preoperative hearing threshold (average 85 dBHL) in the 4th postoperative week, an initial hearing threshold progression of 20-25 dBHL was observed between 0.25 and 1.0 kHz, while of 5-10 dBHL between 2.0-4.0 kHz. Hearing threshold measured in the 6th month showed a slight progression in the range above 1 kHz, but improved by the 12th month, to the results achieved at the 4th week. The effects of cochlear implantation on residual hearing have been studied in numerous studies, in which several key surgical and technical factors have been identified. Nucleus CI532 is a Slim Modiolar electrode profile that is close to the modiolus, so it is expected to have a lower endocochlear hydrodynamic load since it lies in the covering of the osseus spiral lamina, thus less influencing the dynamics of the basilar membrane. However, the perimodiolar location of the electrode array allows the adjacent nerve elements of the spiral ganglion to be stimulated with a lower electrical intensity and a reduced surface that may be neuroprotective. Preservation of acoustic residual hearing following cochlear implantation improves the patient's speech perception and the sound localization skills, particularly in difficult circumstances. Long-term residual hearing preservation may also be of great importance in the subsequent feasibility for regenerative procedures and drug treatments. Orv Hetil. 2018; 159(41): 1680-1688.

摘要

在听力受损患者的康复过程中,通过将植入创伤降至最低,保留人工耳蜗植入后的残余听觉,有助于提高听力表现。要实现这一点,需要采用微创、轻柔的手术方法以及更细、无创伤的电极。在我们目前的研究中,我们报告了一例将Cochlear® Nucleus CI532 Slim Modiolar电极植入一名有残余听力患者的病例。我们的目的是通过听力学监测研究术后残余听觉的可能保留情况。该患者自幼因先天性听力损失,双耳一直佩戴传统的气导式听力矫正装置。在人工耳蜗植入前六个月,我们测量了双耳听力损失的进展情况,因此决定进行人工耳蜗植入。该患者术前双耳均有残余听力,因此使用了Cochlear® Nucleus CI532 Slim Modiolar植入体。通过圆窗入路对患者右耳进行了微创手术。与术后第4周的术前听力阈值(平均85 dBHL)相比,在0.25至1.0 kHz之间观察到初始听力阈值进展了20 - 25 dBHL,而在2.0 - 4.0 kHz之间进展了5 - 10 dBHL。术后第6个月测量的听力阈值在1 kHz以上范围显示有轻微进展,但到第12个月时有所改善,达到了第4周时的结果。众多研究对人工耳蜗植入对残余听力的影响进行了研究,其中确定了几个关键的手术和技术因素。Nucleus CI532是一种靠近蜗轴的Slim Modiolar电极外形,由于它位于骨螺旋板的覆盖层中,预计其内耳流体动力负荷较低,因此对基底膜动力学的影响较小。然而,电极阵列的蜗周位置允许以较低的电强度和减小的表面刺激螺旋神经节的相邻神经元件,这可能具有神经保护作用。人工耳蜗植入后保留残余听觉可改善患者的言语感知和声音定位技能,尤其是在困难情况下。长期保留残余听觉对于后续再生程序和药物治疗的可行性也可能非常重要。《匈牙利医学周报》。2018年;159(41): 1680 - 1688。

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引用本文的文献

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Electrophysiological measurements with electrode types of different perimodiolar properties and the same cochlear implant electronics - a retrospective comparison study.使用具有不同蜗周特性的电极类型和相同人工耳蜗电子设备进行的电生理测量——一项回顾性比较研究。
J Otolaryngol Head Neck Surg. 2019 Sep 6;48(1):46. doi: 10.1186/s40463-019-0361-8.