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关于食物成瘾潜在治疗策略的叙述性综述。

A narrative review of potential treatment strategies for food addiction.

作者信息

Vella Shae-Leigh C, Pai Nagesh B

机构信息

Graduate Medicine, School of Medicine, University of Wollongong, Wollongong, NSW, 2522, Australia.

Wollongong Hospital, Illawarra Shoalhaven Local Health District, Wollongong, NSW, Australia.

出版信息

Eat Weight Disord. 2017 Sep;22(3):387-393. doi: 10.1007/s40519-017-0400-2. Epub 2017 Jun 6.

DOI:10.1007/s40519-017-0400-2
PMID:28589470
Abstract

The concept of food addiction (FA) remains controversial with research being in the nascent stages; FA like any addiction can have a devastating impact on the lives of those afflicted. There exists a clinical need for treatment strategies for those affected. This article reviews potential treatment strategies for FA. The treatment strategies target four core behaviours of the addiction phenotype specifically craving through the opioid system, impulsivity as a personality trait, compulsivity through the serotonergic system and lastly motivation through the dopaminergic system. A range of pharmacological and psychological interventions are reviewed. Future research should seek to test and validate the proposed clinical treatment strategies.

摘要

食物成瘾(FA)的概念仍存在争议,相关研究尚处于初期阶段;与任何成瘾一样,食物成瘾会对患者的生活产生毁灭性影响。临床上需要针对受影响者的治疗策略。本文综述了食物成瘾的潜在治疗策略。这些治疗策略针对成瘾表型的四种核心行为,具体而言,通过阿片系统产生的渴望、作为人格特质的冲动性、通过血清素能系统产生的强迫性以及最后通过多巴胺能系统产生的动机。本文还综述了一系列药物和心理干预措施。未来的研究应致力于测试和验证所提出的临床治疗策略。

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Food Addiction Screening, Diagnosis and Treatment: A Protocol for Residential Treatment of Eating Disorders, Substance Use Disorders and Trauma-Related Psychiatric Comorbidity.食物成瘾筛查、诊断和治疗:饮食障碍、物质使用障碍和与创伤相关的精神共病的住院治疗方案。
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Appetite. 2017 Aug 1;115:1-2. doi: 10.1016/j.appet.2017.03.043. Epub 2017 Mar 30.
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N-acetylcysteine decreases binge eating in a rodent model.N-乙酰半胱氨酸可减少啮齿动物模型中的暴饮暴食行为。
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