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美国男女性生殖器人乳头瘤病毒感染率和疫苗接种率的差异。

Variation in genital human papillomavirus infection prevalence and vaccination coverage among men and women in the USA.

机构信息

Gynecologic Oncology Service, Department of Obstetrics & Gynecology, Womack Army Medical Center, Fort Bragg, NC, USA.

Gynecologic Oncology Service, John P Murtha Cancer Center, Walter Reed National Military Medical Center, Bethesda, MD, USA.

出版信息

Future Oncol. 2017 Jun;13(13):1129-1132. doi: 10.2217/fon-2017-0147. Epub 2017 Jun 7.

DOI:10.2217/fon-2017-0147
PMID:28589730
Abstract

Human papillomavirus (HPV) is the most common sexually transmitted infection that causes majority of anogenital and oropharyngeal cancers. Prophylactic HPV vaccine is available for the primary prevention of cancer and HPV transmission. Here, we are going to discuss the variation of HPV prevalence, HPV vaccination coverage and potential risk factors of men and women, retrieved from the cross-sectional study of the National Health Nutrition Examination Survey, a representative sample of noninstitutionalized, civilian residents in the USA. The overall penile HPV prevalence in men was 45.2% and the high risk oncogenic HPV prevalence defined by DNA testing was 25.1% that appeared to be widespread among all the age groups, which contrasts the vaginal HPV prevalence of 26.8% in women.

摘要

人乳头瘤病毒(HPV)是最常见的性传播感染,可导致大多数肛门生殖器和口咽癌症。预防性 HPV 疫苗可用于癌症和 HPV 传播的一级预防。在这里,我们将讨论从美国代表性的非住院、平民居民的全国健康营养调查的横断面研究中检索到的男性和女性 HPV 流行率、HPV 疫苗接种率和潜在危险因素的变化。男性阴茎 HPV 总流行率为 45.2%,经 DNA 检测定义的高危致癌 HPV 流行率为 25.1%,这似乎在所有年龄段都普遍存在,与女性阴道 HPV 流行率 26.8%形成对比。

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BMJ Open. 2018 Jun 7;8(6):e021170. doi: 10.1136/bmjopen-2017-021170.