人乳头瘤病毒相关癌症
Human Papillomavirus-Related Cancers.
作者信息
Li Yanyun, Xu Congjian
机构信息
Hospital and Institute of Obstetrics and Gynecology, Shanghai Medical College, Fudan University, Shanghai, 200032, People's Republic of China.
出版信息
Adv Exp Med Biol. 2017;1018:23-34. doi: 10.1007/978-981-10-5765-6_3.
Human papillomavirus (HPV) infection is associated with several cancers such as cancer in the cervix, vagina, and vulva and oropharyngeal, anal, penile, and cutaneous carcinomas, which is regarded as a great public health concern. The association between HPV is the strongest with cervical cancer because almost all such malignancies contain viral DNA, notably HPV types 16 and 18. The present chapter summarizes recent progresses of the HPV-associated cancers regarding epidemiology, molecular biology, HPV testing, vaccination, and treatment of HPV-related cancers.
人乳头瘤病毒（HPV）感染与多种癌症相关，如宫颈癌、阴道癌、外阴癌以及口咽癌、肛门癌、阴茎癌和皮肤癌，这被视为一个重大的公共卫生问题。HPV与宫颈癌的关联最为紧密，因为几乎所有此类恶性肿瘤都含有病毒DNA，尤其是16型和18型HPV。本章总结了HPV相关癌症在流行病学、分子生物学、HPV检测、疫苗接种以及HPV相关癌症治疗方面的最新进展。
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