Locks Lindsey M, Reerink Ietje, Tucker Brown Amal, Gnegne Smaila, Ramalanjaona Noelimanjaka, Nanama Simeon, Duggan Christopher P, Garg Aashima
Harvard TH Chan School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA.
United Nations Children's Fund (UNICEF) Headquarters, 3 United Nations Plaza, New York, NY 10017, USA.
Nutrients. 2017 Jun 7;9(6):581. doi: 10.3390/nu9060581.
This study assesses the impact of an integrated infant and young child feeding (IYCF) and micronutrient powder (MNP) intervention on children's risk of anemia and IYCF practices in Madagascar. Quantitative baseline and endline surveys were conducted in representative households with children 6-23 months from two districts, where an 18-month IYCF-MNP intervention was implemented. Relative risks comparing children's risk of anemia and maternal IYCF knowledge and practices at baseline versus endline, and also at endline among MNP-users versus non-users were estimated using log-binomial regression models. 372 and 475 children aged 6-23 months were assessed at baseline and endline respectively. Prevalence of anemia fell from 75.3% to 64.9% from baseline to endline ( = 0.002); the reduction in the risk of anemia remained significant in models adjusting for sociodemographic characteristics (ARR (95% CI): 0.86 (0.78, 0.95), = 0.003). In endline assessments, 229 out of 474 (48.3%) of children had consumed MNPs. MNP-users had a lower risk of anemia (ARR (95% CI): 0.86 (0.74, 0.99), = 0.04) than non-users, after controlling for child's dietary diversity and morbidity, maternal counseling by community-health-workers, and sociodemographic characteristics. Mothers interviewed at endline also had greater nutrition knowledge and were more likely to feed their children ≥4 food groups (ARR (95% CI): 2.92 (2.24, 3.80), < 0.001), and the minimum acceptable diet (ARR (95% CI): 2.88 (2.17, 3.82), < 0.001) than mothers interviewed at baseline. Integration of MNP into IYCF interventions is a viable strategy for improving children's consumption of micronutrients and reducing risk of anemia. The addition of MNP does not negatively impact, and may improve, IYCF practices.
本研究评估了婴幼儿喂养综合干预(IYCF)和微营养素粉(MNP)对马达加斯加儿童贫血风险及婴幼儿喂养习惯的影响。在来自两个地区的有6至23个月儿童的代表性家庭中开展了定量基线调查和终期调查,在这些家庭中实施了为期18个月的IYCF-MNP干预。使用对数二项回归模型估计了比较基线与终期儿童贫血风险以及母亲的IYCF知识和习惯的相对风险,以及终期时MNP使用者与非使用者之间的相对风险。分别在基线和终期评估了372名和475名6至23个月大的儿童。贫血患病率从基线时的75.3%降至终期时的64.9%(P = 0.002);在对社会人口学特征进行调整的模型中,贫血风险的降低仍然显著(调整风险比(95%置信区间):0.86(0.78,0.95),P = 0.003)。在终期评估中,474名儿童中有229名(48.3%)食用了微营养素粉。在控制了儿童的饮食多样性和发病率、社区卫生工作者的母亲咨询以及社会人口学特征后,MNP使用者的贫血风险低于非使用者(调整风险比(95%置信区间):0.86(0.74,0.99),P = 0.04)。在终期接受访谈的母亲也具有更多的营养知识,并且更有可能给孩子提供≥4种食物类别(调整风险比(95%置信区间):2.92(2.24,3.80),P < 0.001),以及最低可接受饮食(调整风险比(95%置信区间):2.88(2.17,3.82),P < 0.001),高于在基线时接受访谈的母亲。将微营养素粉纳入婴幼儿喂养综合干预是改善儿童微量营养素摄入和降低贫血风险的可行策略。添加微营养素粉不会对婴幼儿喂养习惯产生负面影响,甚至可能有所改善。