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改良衰弱指数与阴茎假体植入术后不良结局的关联

Association of the modified frailty index with adverse outcomes after penile prosthesis implantation.

作者信息

Madbouly Khaled, AlHajeri Dulaim, Habous Mohamad, Binsaleh Saleh

机构信息

a Department of Urology , Prince Mohammed Bin Abdulaziz Hospital , Riyadh , Saudi Arabia.

b Division of Urology , Department of Surgery, Faculty of Medicine, King Saud University , Riyadh , Saudi Arabia , and.

出版信息

Aging Male. 2017 Jun;20(2):119-124. doi: 10.1080/13685538.2017.1292499. Epub 2017 Feb 28.

Abstract

OBJECTIVES

To investigate frailty as a predictor of surgical outcome in elderly patients undergoing penile prosthesis implantation.

MATERIAL AND METHODS

A total of 54 elderly patients, above 60 years of age, underwent penile prosthesis implantation between 2012 and 2014. Their data were collected and retrospectively analyzed. A modified frailty index (mFI) was calculated for each patient based on 11 risk factors from the Canadian Study of Health and Aging Frailty Index. The 1-year adverse outcomes were correlated with mFI, patients' and procedure's risk factors.

RESULTS

Mean age was 64.9 ± 5.2 years. No mortality was reported in our patients, however, one-year adverse outcomes were encountered in 43 (79.6%) patients. Among all studied variables, the 1-year adverse outcomes was not significantly association with mFI, but with preoperative glycosylated hemoglobin A1c (HbA1c) (p = 0.031) and associated Peyronie's disease (PD) (p = 0.000). HbA1c, dyslipidemia, hypertension, PD and duration of the procedure were predictive of infection complications (p < 0.05). Only PD and HbA1c sustained an independent significant impact.

CONCLUSIONS

mFI is not a predictive of post-penile prosthesis implantation adverse outcomes in elderly patients with impotence. Degree of diabetic control and association with PD was associated with the 1-year adverse outcomes and infection complications.

摘要

目的

探讨衰弱作为老年阴茎假体植入患者手术预后预测指标的价值。

材料与方法

2012年至2014年间,共有54例60岁以上老年患者接受了阴茎假体植入手术。收集他们的数据并进行回顾性分析。根据加拿大健康与衰老研究衰弱指数中的11项危险因素,为每位患者计算改良衰弱指数(mFI)。将1年不良结局与mFI、患者及手术相关危险因素进行相关性分析。

结果

患者平均年龄为64.9±5.2岁。本研究患者中未报告死亡病例,然而,43例(79.6%)患者出现了1年不良结局。在所有研究变量中,1年不良结局与mFI无显著相关性,但与术前糖化血红蛋白A1c(HbA1c)(p = 0.031)及合并佩罗尼氏病(PD)(p = 0.000)有关。HbA1c、血脂异常、高血压、PD及手术时间是感染并发症的预测因素(p < 0.05)。只有PD和HbA1c具有独立的显著影响。

结论

mFI不能预测老年阳痿患者阴茎假体植入术后的不良结局。糖尿病控制程度及与PD的合并情况与1年不良结局及感染并发症相关。

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