Baird Bryce A, Parikh Kevin, Broderick Gregory
Mayo Clinic Florida, Jacksonville, FL, USA.
Transl Androl Urol. 2021 Oct;10(10):3873-3884. doi: 10.21037/tau-21-568.
We aim to review and summarize published literature that features implanted penile devices and details infection of these devices as a complication. In particular, we will detail the factors that influence infection of penile implants.
Types of penile prostheses (PP) include inflatable implants and semirigid implants; these are utilized for treatment of erectile dysfunction. Likely the most feared complication of penile implants is infection. There are a handful of factors that are implicated in device infection.
Searches were performed using MEDLINE and PubMed databases using keywords and phrases 'penile implant AND infection'; 'penile prosthesis AND infection'; 'penile implant infection'. We have presented results from our literature search. We divided these into 'Surgical Elements' and 'Patient Selection and Factors.' Each topic is discussed in its own section.
Strides have been made since the initial penile prosthesis (IPP) surgeries to improve infection rates including diabetes control, antibiotic coating of devices, and antibiotic implementation. Going forward, more studies, especially randomized control trials, need to focus on defining levels of diabetic control (sugar control and A1C control), determining the role of metabolic syndrome in infection promotion and determining laboratory values which could be predictive of infection. We present a discussion of important factors to consider in the realm of PP infections. In addition, we include studies which discuss topics for future directions in decreasing the number of infections seen with PP.
我们旨在回顾和总结已发表的有关植入式阴茎装置的文献，并详细阐述这些装置感染作为一种并发症的情况。特别是，我们将详细说明影响阴茎植入物感染的因素。
阴茎假体（PP）的类型包括可膨胀植入物和半刚性植入物；这些用于治疗勃起功能障碍。阴茎植入物最令人担忧的并发症可能是感染。有一些因素与装置感染有关。
使用MEDLINE和PubMed数据库进行检索，关键词和短语为“阴茎植入物与感染”；“阴茎假体与感染”；“阴茎植入物感染”。我们展示了文献检索的结果。我们将这些结果分为“手术因素”和“患者选择与因素”。每个主题在各自的部分进行讨论。
自最初的阴茎假体（IPP）手术以来，在提高感染率方面已经取得了进展，包括糖尿病控制、装置的抗生素涂层以及抗生素的应用。展望未来，更多的研究，尤其是随机对照试验，需要专注于确定糖尿病控制水平（血糖控制和糖化血红蛋白控制）、确定代谢综合征在促进感染中的作用以及确定可预测感染的实验室值。我们对阴茎假体感染领域中需要考虑的重要因素进行了讨论。此外，我们纳入了一些讨论未来降低阴茎假体感染数量方向的研究。
