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颈椎前路融合术后相邻节段疾病治疗的不同手术方法:49例患者的回顾性研究

Different surgical approaches for the treatment of adjacent segment diseases after anterior cervical fusion: A retrospective study of 49 patients.

作者信息

Wang Feng, Wang Peng, Miao De-Chao, Du Wei, Shen Yong

机构信息

Department of Spine Surgery, Hebei Provincial Key Laboratory of Orthopedic Biomechanics, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

出版信息

Medicine (Baltimore). 2017 Jun;96(23):e7042. doi: 10.1097/MD.0000000000007042.

Abstract

Studies in the literature have not delineated the surgical approaches of symptomatic adjacent segment diseases (ASDs) in patients undergoing reoperation after an initial anterior cervical fusion (ACF). The purpose of this study was to determine the optimal surgical approaches of ASD and the incidence of the dysphagia after reoperation.This was a retrospective study of 49 patients with ASD after an initial ACF surgery, which had undergone a reoperation at our medical center between January 2010 and December 2014. The surgical approaches were used by anterior cervical discectomy and fusion (ACDF), ACDF with the Zero-profile device, laminoplasty, and laminectomy with internal fixation. Patients were classified according to the different surgical approaches of anterior (n = 38) versus posterior (n = 11) groups and ACDF (n = 25) versus Zero-P (n = 13) groups. Clinical evaluations were performed preoperatively and repeated in 24 months after operation.This retrospective study included 26 men and 23 women with a mean age at revision surgery of 54.3 years and ASD onset time of 7.3 years. The patients were followed up with an average of 4.1 years. The reoperation rate was 5.4% in this study. The Japanese Orthopaedic Association (JOA), Neck Disability Index (NDI), and visual analogue scale (VAS) scores demonstrated significant improvements compared with preoperative in both anterior and posterior groups (P < .05). However, there were no differences between the 2 groups (P > .05). The operation time of ACDF group was more than Zero-P group, with significant differences (P < .05). However, there were no differences in JOA, NDI, and VAS scores between the ACDF and Zero-P groups pre- and postoperative (P > .05). A total of 12 (24.5%) patients had dysphagia after reoperation. The incidence of dysphagia in Zero-P group (1/13) was less than ACDF group (11/25), with significant differences (P < .05). There were no cases of major neurological or vascular complications, and wound complications.The clinical situation, initial operation, and secondary preoperative imaging findings were analyzed comprehensively, anterior or posterior approach were chosen, which can effectively relieve spinal cord compression and improve spinal cord function. In ACDF with the Zero-profile device surgery, there was no need to remove the previous internal fixation, shorten the operation time, and reduce the incidence of postoperative dysphagia.

摘要

文献研究尚未明确初次颈椎前路融合术(ACF)后再次手术患者中症状性相邻节段疾病(ASD)的手术入路。本研究的目的是确定ASD的最佳手术入路以及再次手术后吞咽困难的发生率。

这是一项对49例初次ACF手术后发生ASD且于2010年1月至2014年12月在我们医疗中心接受再次手术患者的回顾性研究。手术入路包括颈椎前路椎间盘切除融合术(ACDF)、使用Zero-profile装置的ACDF、椎板成形术以及椎板切除内固定术。患者根据前路(n = 38)与后路(n = 11)组以及ACDF(n = 25)与Zero-P(n = 13)组的不同手术入路进行分类。术前进行临床评估,并在术后24个月重复评估。

这项回顾性研究包括26名男性和23名女性,再次手术时的平均年龄为54.3岁,ASD发病时间为7.3年。患者平均随访4.1年。本研究中的再次手术率为5.4%。日本骨科协会(JOA)、颈部功能障碍指数(NDI)和视觉模拟量表(VAS)评分显示,前后两组与术前相比均有显著改善(P <.05)。然而,两组之间无差异(P >.05)。ACDF组的手术时间比Zero-P组长,差异有统计学意义(P <.05)。然而,ACDF组和Zero-P组术前和术后的JOA、NDI和VAS评分无差异(P >.05)。共有12例(24.5%)患者再次手术后出现吞咽困难。Zero-P组(1/13)吞咽困难的发生率低于ACDF组(11/25),差异有统计学意义(P <.05)。未发生重大神经或血管并发症以及伤口并发症。

综合分析临床情况、初次手术及二次术前影像学表现,选择前路或后路手术入路,可有效解除脊髓压迫并改善脊髓功能。在使用Zero-profile装置的ACDF手术中,无需拆除先前的内固定,缩短了手术时间,并降低了术后吞咽困难的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a962/5466215/f07604f01d0e/medi-96-e7042-g001.jpg

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