Kalkan Kamuran, Hamur Hikmet, Yildirim Erkan, Ipek Emrah, Ermis Emrah, Ozturk Mustafa, Karal Huseyin, Korkmaz Ali Fuat, Bayantemur Murat, Demirelli Selami
1 Department of Cardiology, University of Health Sciences, Erzurum Education and Research Hospital, Erzurum, Turkey.
2 Department of Cardiology, Erzincan University Faculty of Medicine, Erzincan, Turkey.
Angiology. 2018 Feb;69(2):158-163. doi: 10.1177/0003319717712118. Epub 2017 Jun 8.
Syntax score (SS) and Gensini score (GS) are used to determine the complexity and severity of coronary artery disease. Although there are some studies indicating the individual relationship of these scoring systems with the carotid intima-media thickness (cIMT) and epicardial fat tissue (EFT), there was no previous study that compared the SS and GS in that respect. We aimed to assess the relationship of SS and GS with predictors of atherosclerosis. We enrolled 522 patients. There were positive correlations between GS and SS tertiles with cIMT and EFT. According to multivariate linear regression analysis for GS, EFT (β: 0.035, t: 2.63, and P = .49) and cIMT (β: 0.339, t: 2.97, and P = .053) were not independently associated. For SS, EFT (β: 0.009, t: 6.5, and P = .006) and cIMT (β: 1.2, t: 10.1, and P = .001) were independently and significantly associated. We showed that the SS is significantly associated more with surrogate markers of atherosclerosis such as EFT and cIMT than the GS.
句法评分(SS)和Gensini评分(GS)用于确定冠状动脉疾病的复杂性和严重程度。虽然有一些研究表明这些评分系统与颈动脉内膜中层厚度(cIMT)和心外膜脂肪组织(EFT)之间存在个体关系,但之前尚无在这方面比较SS和GS的研究。我们旨在评估SS和GS与动脉粥样硬化预测指标之间的关系。我们纳入了522例患者。GS和SS三分位数与cIMT和EFT之间存在正相关。根据对GS的多变量线性回归分析,EFT(β:0.035,t:2.63,P = 0.49)和cIMT(β:0.339,t:2.97,P = 0.053)并非独立相关。对于SS,EFT(β:0.009,t:6.5,P = 0.006)和cIMT(β:1.2,t:10.1,P = 0.001)独立且显著相关。我们表明,与GS相比,SS与动脉粥样硬化的替代标志物如EFT和cIMT的相关性更强。