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肌肉力量差对老年人急性病期间及康复后临床和服务结局的影响。

Impact of poor muscle strength on clinical and service outcomes of older people during both acute illness and after recovery.

作者信息

Gariballa Salah, Alessa Awad

机构信息

Department of Internal Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, PO Box 17666, Al-Ain, United Arab Emirates.

University of Sheffield, Sheffield, UK.

出版信息

BMC Geriatr. 2017 Jun 7;17(1):123. doi: 10.1186/s12877-017-0512-6.

Abstract

BACKGROUND

Although Low muscle strength is an important predictor of functional decline in older people, however information on its impact on clinical and service outcomes in acute care settings is still lacking. The aim of this study is to measure the impact of low muscle strength on clinical and service outcomes in older adults during both acute illness and recovery.

METHODS

Randomly selected 432 hospitalised older patients had their clinical characteristics and nutritional status assessed within 72 h of admission, at 6 weeks and at 6 months. Low muscle strength-hand grip was defined using the European Working Group criteria. Health outcome measures including nutritional status, length of hospital stay, disability, discharge destination, readmission and mortality were also measured.

RESULTS

Among the 432 patients recruited, 308 (79%) had low muscle strength at baseline. Corresponding figures at 6 weeks and at 6 months were 140 (73%) and 158 (75%). Patients with poor muscle strength were significantly older, increasingly disabled, malnourished and stayed longer in hospital compared with those with normal muscle strength. A significantly higher number of patients with normal muscle strength discharged home independently compared with those with poor muscle strength (p < 0.05). One-year death rate was lower in patients with normal muscle strength 5(6%), compared with those with poor muscle strength 52(15%), however, results were not statistically significant after adjusting for other poor prognostic indicators [adjusted hazard ratio 0.74 (95% CI: 0.14-3.87), p = 0.722].

CONCLUSION

Poor muscle strength in older people is associated with poor clinical service outcomes during both acute illness and recovery.

摘要

背景

尽管肌肉力量低下是老年人功能衰退的重要预测指标,但关于其对急性护理环境中临床和服务结局的影响的信息仍然缺乏。本研究的目的是测量肌肉力量低下对老年人在急性疾病期间和康复过程中临床和服务结局的影响。

方法

随机选取432例住院老年患者,在入院后72小时内、6周和6个月时评估其临床特征和营养状况。采用欧洲工作组标准定义肌肉力量低下——握力。还测量了包括营养状况、住院时间、残疾情况、出院去向、再入院和死亡率在内的健康结局指标。

结果

在招募的432例患者中,308例(79%)在基线时肌肉力量低下。6周和6个月时的相应数字分别为140例(73%)和158例(75%)。与肌肉力量正常的患者相比,肌肉力量差的患者年龄明显更大,残疾程度更高,营养不良,住院时间更长。与肌肉力量差的患者相比,肌肉力量正常的患者独立出院回家的人数明显更多(p<0.05)。肌肉力量正常的患者1年死亡率为5(6%),低于肌肉力量差的患者52(15%),然而,在调整其他不良预后指标后,结果无统计学意义[调整后风险比0.74(95%CI:0.14 - 3.87),p = 0.722]。

结论

老年人肌肉力量差与急性疾病期间和康复过程中的不良临床服务结局相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b92/5463384/9e98b63d8e0e/12877_2017_512_Fig1_HTML.jpg

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