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非裔美国人的理想心血管健康与外周动脉疾病:杰克逊心脏研究的结果

Ideal cardiovascular health and peripheral artery disease in African Americans: Results from the Jackson Heart Study.

作者信息

Collins Tracie C, Slovut David P, Newton Robert, Johnson William D, Larrivee Sandra, Patterson Jeremy, Johnston Judy A, Correa Adolfo

机构信息

Department of Preventive Medicine and Public Health, University of Kansas Medical Center, School of Medicine, Wichita, KS, United States.

Division of Cardiology, Department of Medicine, Department of Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Bronx, NY, United States.

出版信息

Prev Med Rep. 2017 May 18;7:20-25. doi: 10.1016/j.pmedr.2017.05.005. eCollection 2017 Sep.

Abstract

We sought to determine the association of Life's Simple Seven (LSS) with peripheral artery disease (PAD) in African Americans. We performed a cross-sectional analysis of baseline data (2000-2004) from subjects participating in the Jackson Heart Study. African American men and women (N = 4403) age 35-84 years participated in the study. PAD was defined by an ankle-brachial index (ABI) of < 0.9. We assessed frequency of LSS (body mass index [BMI], blood pressure, total cholesterol, glucose, dietary habits, physical activity, and smoking) among participants with and without PAD. LSS variables were categorized as ideal, intermediate, or poor to indicate a participant's health status. Data were analyzed using logistic regression to assess the association of PAD with LSS. PAD was diagnosed in 113 participants (2.6%). The percentage of the cohort meeting criteria for ideal health for each of the seven LSS factors was: 14.2% for BMI, 17.1% for blood pressure, 38.0% for total cholesterol, 72.9% for glucose, 1.0% for dietary habits, 19.2% for physical activity, and 84.6% for smoking. Having ≥ 3 LSS variables within the category of poor health was associated with elevated odds for PAD (odds ratio (OR) 1.34, 95% CI 1.11-1.63) after adjusting for age. Among African American adults, LSS variables are associated with PAD. Further studies are needed to determine the association of LSS with PAD among other racial/ethnic groups.

摘要

我们试图确定“生命简单七要素”(LSS)与非裔美国人外周动脉疾病(PAD)之间的关联。我们对参与杰克逊心脏研究的受试者的基线数据(2000 - 2004年)进行了横断面分析。年龄在35 - 84岁的非裔美国男性和女性(N = 4403)参与了该研究。PAD通过踝臂指数(ABI)< 0.9来定义。我们评估了有和没有PAD的参与者中LSS(体重指数[BMI]、血压、总胆固醇、血糖、饮食习惯、身体活动和吸烟)的情况。LSS变量被分类为理想、中等或较差,以表明参与者的健康状况。使用逻辑回归分析数据,以评估PAD与LSS之间的关联。113名参与者(2.6%)被诊断为PAD。该队列中符合七个LSS因素中每个因素理想健康标准的百分比分别为:BMI为14.2%,血压为17.1%,总胆固醇为38.0%,血糖为72.9%,饮食习惯为1.0%,身体活动为19.2%,吸烟为84.6%。在调整年龄后,健康状况较差类别中有≥ 3个LSS变量与PAD的患病几率升高相关(优势比[OR] 1.34,95%可信区间1.11 - 1.63)。在非裔美国成年人中,LSS变量与PAD相关。需要进一步研究以确定LSS与其他种族/族裔群体中PAD的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f2/5447374/f1935c731953/gr1.jpg

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