德国八所大学医院内科医生在药物基因组学临床决策支持方面的经验。
The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals.
作者信息
Hinderer Marc, Boeker Martin, Wagner Sebastian A, Binder Harald, Ückert Frank, Newe Stephanie, Hülsemann Jan L, Neumaier Michael, Schade-Brittinger Carmen, Acker Till, Prokosch Hans-Ulrich, Sedlmayr Brita
机构信息
Chair of Medical Informatics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Faculty of Medicine & Medical Center, Institute of Medical Biometry & Statistics, University of Freiburg, Freiburg, Germany.
出版信息
Pharmacogenomics. 2017 Jun;18(8):773-785. doi: 10.2217/pgs-2017-0027. Epub 2017 Jun 8.
AIM
The aim of this study was to assess the physicians' attitude, their knowledge and their experience in pharmacogenomic clinical decision support in German hospitals.
MATERIALS & METHODS: We conducted an online survey to address physicians of 13 different medical specialties across eight German university hospitals. In total, 564 returned questionnaires were analyzed.
RESULTS
The remaining knowledge gap, the uncertainty of test reimbursement and the physicians' lack of awareness of existing pharmacogenomic clinical decision support systems (CDSS) are the major barriers for implementing pharmacogenomic CDSS into German hospitals. Furthermore, pharmacogenomic CDSS are most effective in the form of real-time decision support for internists.
CONCLUSION
Physicians in German hospitals require additional education of both genetics and pharmacogenomics. They need to be provided with access to relevant pharmacogenomic CDSS.
目的
本研究旨在评估德国医院医生在药物基因组学临床决策支持方面的态度、知识和经验。
材料与方法
我们开展了一项在线调查，对象为德国八所大学医院13个不同医学专业的医生。总共分析了564份回收的问卷。
结果
尚存的知识差距、检测报销的不确定性以及医生对现有药物基因组学临床决策支持系统（CDSS）缺乏认识，是德国医院实施药物基因组学CDSS的主要障碍。此外，药物基因组学CDSS以内科医生实时决策支持的形式最为有效。
结论
德国医院的医生需要接受遗传学和药物基因组学方面的额外教育。需要为他们提供使用相关药物基因组学CDSS的机会。
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