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单核细胞增生李斯特菌生物膜的抑制策略——当前认知与未来展望

Inhibition strategies of Listeria monocytogenes biofilms-current knowledge and future outlooks.

作者信息

Oloketuyi Sandra F, Khan Fazlurrahman

机构信息

Department of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida, U.P., India.

出版信息

J Basic Microbiol. 2017 Sep;57(9):728-743. doi: 10.1002/jobm.201700071. Epub 2017 Jun 8.

DOI:10.1002/jobm.201700071
PMID:28594071
Abstract

There is an increasing trend in the food industry on the Listeria monocytogenes biofilm formation and inhibition. This is attributed to its easy survival on contact surfaces, resistance to disinfectants or antibiotics and growth under the stringent condition used for food processing and preservation thereby leading to food contamination products by direct or indirect exposure. Though, there is a lack of conclusive evidences about the mechanism of biofilm formation, in this review, the concept of biofilm formation and various chemical, physical, and green technology approaches to prevent or control the biofilm formed is discussed. State-of-the-art approaches ranging from the application of natural to synthetic molecules with high effectiveness and non-toxicity targeted at the different steps of biofilm formation could positively influence the biofilm inhibition in the future.

摘要

食品工业中,针对单核细胞增生李斯特菌生物膜形成及抑制的研究呈上升趋势。这归因于它易于在接触表面存活、对消毒剂或抗生素具有抗性,以及能在食品加工和保存的严苛条件下生长,从而通过直接或间接接触导致食品污染。尽管关于生物膜形成机制尚无确凿证据,但在本综述中,将讨论生物膜形成的概念以及预防或控制生物膜形成的各种化学、物理和绿色技术方法。从应用天然分子到合成分子,针对生物膜形成不同阶段的高效且无毒的前沿方法,有望在未来对生物膜抑制产生积极影响。

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