Alrahbi Sufyan, Alaraimi Rashid, Alzaabi Abdalla, Gosselin Sophie
*Emergency Medicine Residency Program, Faculty of Medicine,McGill University,Montreal,QC.
†Department of Medicine,McGill University Health Centre,Montréal,QC.
CJEM. 2018 Mar;20(2):256-259. doi: 10.1017/cem.2017.35. Epub 2017 Jun 9.
Clinical question Is intensive blood pressure (BP) treatment (systolic BP target 110-139 mm Hg) better than standard antihypertensive treatment (systolic BP target 140-179 mm Hg) in reducing mortality and disability in patients with acute intracerebral hemorrhage (ICH)? Article chosen Qureshi AI, Palesch YY, Barsan WG, et al. Intensive blood-pressure lowering in patients with acute cerebral hemorrhage. N Engl J Med 2016;375(11):1033-43.
To determine the therapeutic benefit of intensive BP treatment compared to standard BP treatment in reducing death and disability after 3 months of follow-up among patients with ICH treated within 4.5 hours from onset of symptoms.
临床问题 在降低急性脑出血(ICH)患者的死亡率和残疾率方面,强化血压(BP)治疗(收缩压目标为110 - 139 mmHg)是否优于标准抗高血压治疗(收缩压目标为140 - 179 mmHg)?所选文章 库雷希·艾,帕莱施·YY,巴尔桑·WG等。急性脑出血患者强化降压治疗。《新英格兰医学杂志》2016年;375(11):1033 - 43。
确定在症状发作4.5小时内接受治疗的ICH患者中,与标准BP治疗相比,强化BP治疗在3个月随访后降低死亡和残疾方面的治疗益处。