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老年人中胆钙化醇(维生素D₃)与麦角钙化醇(维生素D₂)的比较

Cholecalciferol (D₃) Versus Ergocalciferol (D₂) in Older Adults.

作者信息

Dereje Simona, Muradov Ilan, Nazzal Samira, Nguyen Timothy

出版信息

Consult Pharm. 2017 Jun 1;32(6):337-339. doi: 10.4140/TCP.n.2017.337.

DOI:10.4140/TCP.n.2017.337
PMID:28595683
Abstract

Vitamin D is a fat-soluble vitamin that is naturally found in very few food sources. It is produced endogenously from ultraviolet light from the sun striking the skin and then triggering vitamin D synthesis and activation. Vitamin D helps promote calcium absorption in the gut, maintains adequate serum calcium and phosphate levels, promotes bone growth, modulates cell growth, and has many other roles. There have been an increasing number of people, especially in older adults, with vitamin D deficiency. This is in part a result of a reduction of sun exposure as people age, increase in use of sunscreen, and other factors. This article highlights the roles of cholecalciferol (vitamin D3) versus ergocalciferol (vitamin D2) supplementation for practicing pharmacists.

摘要

维生素D是一种脂溶性维生素,天然存在于极少的食物来源中。它由阳光中的紫外线照射皮肤后内源性产生,进而触发维生素D的合成与活化。维生素D有助于促进肠道对钙的吸收,维持血清钙和磷水平充足,促进骨骼生长,调节细胞生长,还有许多其他作用。维生素D缺乏的人数一直在增加,尤其是老年人。这部分是由于人们随着年龄增长日照减少、防晒霜使用增加以及其他因素所致。本文重点介绍了胆钙化醇(维生素D3)与麦角钙化醇(维生素D2)补充剂对执业药师的作用。

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Biomedicines. 2025 Apr 21;13(4):1002. doi: 10.3390/biomedicines13041002.
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Lactobacillus rhamnosus GG Promotes Intestinal Vitamin D Absorption by Upregulating Vitamin D Transporters in Senile Osteoporosis.罗伊氏乳杆菌 GG 通过上调老年性骨质疏松症中维生素 D 转运蛋白促进肠道维生素 D 吸收。
Calcif Tissue Int. 2022 Aug;111(2):162-170. doi: 10.1007/s00223-022-00975-z. Epub 2022 May 26.
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Is there a window of opportunity for the therapeutic use of vitamin D in multiple sclerosis?
维生素D用于治疗多发性硬化症是否存在治疗时机窗?
Neural Regen Res. 2022 Sep;17(9):1945-1954. doi: 10.4103/1673-5374.335139.
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Vitamin D retards intervertebral disc degeneration through inactivation of the NF-κB pathway in mice.维生素D通过使小鼠体内的核因子κB信号通路失活来延缓椎间盘退变。
Am J Transl Res. 2019 Apr 15;11(4):2496-2506. eCollection 2019.