James P N, Anderson J B, Prior J G, White J P, Henry J A, Cochrane G M
Postgrad Med J. 1985 Jan;61(711):7-10. doi: 10.1136/pgmj.61.711.7.
A questionnaire on the pattern of drug taking was completed by 185 patients with chronic airflow obstruction. Of these, 49% admitted to taking their prescribed therapy regularly and 33% could be regarded as being fully compliant. The use of increasing numbers of drugs was not accompanied by a fall in compliance. Regular drug taking was better in patients (particularly females) with asthma than in patients with chronic bronchitis and emphysema. During acute exacerbations of airflow obstruction, excessive use of bronchodilators beyond the recommended increase in medication was rare; indeed, underuse of therapy in this situation was commoner. These conclusions must be regarded as tentative since the questionnaire was not validated by repeat interviewing or measurement of drug usage.
185例慢性气流阻塞患者完成了一份关于用药模式的调查问卷。其中，49%的患者承认定期服用规定的药物治疗，33%的患者可被视为完全依从。使用药物数量的增加并没有伴随着依从性的下降。哮喘患者（尤其是女性）的规律用药情况优于慢性支气管炎和肺气肿患者。在气流阻塞急性加重期间，超出推荐增加剂量过度使用支气管扩张剂的情况很少见；事实上，在这种情况下治疗不足更为常见。由于该调查问卷未通过重复访谈或药物使用测量进行验证，因此这些结论必须被视为初步结论。
