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点头症备受关注——近期研究结果的透视。

Nodding Syndrome in the Spotlight - Placing Recent Findings in Perspective.

机构信息

Department of Neurology, School of Medicine, and Oregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, USA.

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

出版信息

Trends Parasitol. 2017 Jul;33(7):490-492. doi: 10.1016/j.pt.2017.05.001. Epub 2017 Jun 6.

Abstract

Nodding syndrome (NS) is a debated scientific topic. A recently published study suggests that NS is an autoimmune disorder based on findings of cross-reacting antibodies between neuronal structures and a protein present in Onchocerca volvulus (OV). In our opinion, the proposed causal relationship between OV infection and NS has yet to be demonstrated and, instead, OV infection in NS may be opportunistic.

摘要

点头综合征(NS)是一个备受争议的科学议题。最近发表的一项研究表明,NS 是一种自身免疫性疾病,其依据是神经元结构与存在于旋盘尾丝虫(OV)中的一种蛋白之间存在交叉反应抗体。在我们看来,OV 感染与 NS 之间的因果关系尚未得到证实,而 NS 中的 OV 感染可能是机会性的。

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本文引用的文献

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Nodding syndrome: 2015 International Conference Report and Gulu Accord.点头综合征:2015年国际会议报告与古卢协议
eNeurologicalSci. 2015 Nov 7;3:80-83. doi: 10.1016/j.ensci.2015.11.001. eCollection 2016 Jun.
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Nodding syndrome.点头症。
Emerg Infect Dis. 2013;19(9):1374-84. doi: 10.3201/eid1909.130401.
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The head nodding syndrome--clinical classification and possible causes.点头综合征——临床分类及可能病因
Epilepsia. 2008 Dec;49(12):2008-15. doi: 10.1111/j.1528-1167.2008.01671.x. Epub 2008 May 21.

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