Gilman Marina, Petty Brian, Maira Carissa, Pethan Madeleine, Wang Lijia, Hapner Edie R, Johns Michael M
Emory Voice Center, Department of Otolaryngology Head and Neck Surgery, Emory University, Atlanta, Georgia.
Emory Voice Center, Department of Otolaryngology Head and Neck Surgery, Emory University, Atlanta, Georgia.
J Voice. 2017 Sep;31(5):545-549. doi: 10.1016/j.jvoice.2016.11.001. Epub 2017 Jun 7.
A recently published retrospective chart review of aerodynamic profiles of women with primary muscle tension dysphonia by Gillespie et al (2013) identified various relationships between mean airflow rate (MFR) and estimated subglottal pressure (est-Psub). The current retrospective study expanded the diagnostic categories to include all voice disorders referred for voice therapy. Three research questions were proposed: (1) Are there differences in the MFR and the est-Psub compared with the normal control group? (2) Within the disordered population, are there different variations in the pairing of MFR and est-Psub? (3) If these variations exist, are they diagnosis specific?
A retrospective chart review of patients seen for acoustic and aerodynamic voice assessment at the Emory Voice Center between January 1, 2013 and December 31, 2014, were examined for aerodynamic measures of est-Psub and MFR; of these, 192 met the inclusion criteria. Simple t test, two-step cluster analysis, and analysis of variance, as well as Tukey multiple comparisons, were performed using R and SPSS.
Mean est-Psub was significantly greater in the group with voice disorder than in the control group (P value < 0.001). However, no statistical significance was found when comparing the MFR with the control group (P value <0.59). Nine possible pairings of MFR and est-Psub were found. Sufficient evidence was not found to detect significant differences in these pairings across diagnostic groups.
With regard to the rate and interrelationships of MFR and est-Psub, the findings of this study are similar to those of Gillespie et al, that is, MFR and est-Psub are not determinate of diagnosis.
吉莱斯皮等人（2013年）最近发表的一项关于原发性肌肉紧张性发声障碍女性患者空气动力学特征的回顾性图表分析，确定了平均气流率（MFR）与估计声门下压力（est-Psub）之间的各种关系。当前的回顾性研究扩大了诊断类别，将所有转诊接受嗓音治疗的嗓音障碍纳入其中。提出了三个研究问题：（1）与正常对照组相比，MFR和est-Psub是否存在差异？（2）在嗓音障碍人群中，MFR和est-Psub的配对是否存在不同变化？（3）如果存在这些变化，它们是否具有诊断特异性？
对2013年1月1日至2014年12月31日在埃默里嗓音中心接受声学和空气动力学嗓音评估的患者进行回顾性图表分析，以检测est-Psub和MFR的空气动力学指标；其中192例符合纳入标准。使用R和SPSS进行单样本t检验、两步聚类分析、方差分析以及Tukey多重比较。
嗓音障碍组的平均est-Psub显著高于对照组（P值<0.001）。然而，将MFR与对照组进行比较时未发现统计学意义（P值<0.59）。发现了MFR和est-Psub的九种可能配对。未找到足够证据来检测这些配对在不同诊断组之间的显著差异。
关于MFR和est-Psub的速率及相互关系，本研究结果与吉莱斯皮等人的研究相似，即MFR和est-Psub不能作为诊断依据。
