University of Pittsburgh, Pittsburgh, PA, USA.
J Speech Lang Hear Res. 2013 Apr;56(2):481-8. doi: 10.1044/1092-4388(2012/11-0217). Epub 2012 Sep 19.
In this study, the authors aimed to (a) determine whether phonatory airflows and estimated subglottal pressures (est-Psub) for women with primary muscle tension dysphonia/aphonia (MTD/A) differ from those for healthy speakers; (b) identify different aerodynamic profile patterns within the MTD/A subject group; and (c) determine whether results suggest new understanding of pathogenesis in MTD/A.
Retrospective review of aerodynamic data collected from 90 women at the time of primary MTD/A diagnosis.
Aerodynamic profiles were significantly different for women with MTD/A as compared with healthy speakers. Five distinct profiles were identified: (a) normal flow, normal est-Psub; (b) high flow, high est-Psub; (c) low flow, normal est-Psub; (d) normal flow, high est-Psub; and (e) high flow, normal est-Psub.
This study is the first to identify distinct subgroups of aerodynamic profiles in women with MTD/A and to quantitatively identify a clinical phenomenon sometimes described in association with it-"breath holding"-that is shown by low airflow with normal est-Psub. Results were consistent with clinical claims that diverse respiratory and laryngeal functions may underlie phonatory patterns associated with MTD/A. One potential mechanism, based in psychobiological theory, is introduced to explain some of the variability in aerodynamic profiles of women with MTD/A.
本研究旨在：(a) 确定原发性肌肉紧张性发声障碍/失音（MTD/A）女性的发声气流和估计的声门下压（est-Psub）是否与健康发音者不同；(b) 确定 MTD/A 受试者组内不同的空气动力学特征模式；(c) 确定结果是否提示对 MTD/A 发病机制的新认识。
回顾性分析 90 名原发性 MTD/A 女性诊断时的空气动力学数据。
与健康发音者相比，MTD/A 女性的空气动力学特征明显不同。确定了五种不同的特征模式：(a) 正常气流，正常 est-Psub；(b) 高气流，高 est-Psub；(c) 低气流，正常 est-Psub；(d) 正常气流，高 est-Psub；和 (e) 高气流，正常 est-Psub。
本研究首次在 MTD/A 女性中确定了空气动力学特征的不同亚组，并定量确定了与呼吸有关的临床现象“屏气”-表现为低气流但 est-Psub 正常。结果与临床声称一致，即不同的呼吸和喉部功能可能是与 MTD/A 相关的发声模式的基础。根据心理生物学理论，引入了一种潜在机制来解释 MTD/A 女性空气动力学特征的一些可变性。
