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将人文方法应用于癌症临床试验。

Bringing a humanistic approach to cancer clinical trials.

作者信息

Arai Roberto Jun, Longo Elaine Santana, Sponton Maria Helena, Del Pilar Estevez Diz Maria

机构信息

Núcleo de Pesquisa, Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina da Universidade de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo 01246-000, Brazil.

出版信息

Ecancermedicalscience. 2017 May 18;11:738. doi: 10.3332/ecancer.2017.738. eCollection 2017.

DOI:10.3332/ecancer.2017.738
PMID:28596804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5440181/
Abstract

In this article, we describe some practical aspects that promote the humanisation of clinical research. Actions are not limited to improving the communication skills of medical staff but also include maintenance of care continuity, accessible written information, and application of theoretic models such as shared decision-making and management of stress in decision-making under uncertainty. We believe that a comprehensive strategy will increase patients' motivation to participate in and adhere to clinical research.

摘要

在本文中,我们描述了一些促进临床研究人性化的实际方面。行动不仅限于提高医务人员的沟通技巧,还包括维持护理连续性、提供易于获取的书面信息,以及应用诸如共同决策和在不确定性下决策时的压力管理等理论模型。我们相信,一项全面的策略将提高患者参与和坚持临床研究的积极性。

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本文引用的文献

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Int J Clin Health Psychol. 2015 Jan-Apr;15(1):76-80. doi: 10.1016/j.ijchp.2014.11.001. Epub 2014 Nov 28.
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Patient perspectives on the barriers associated with medication adherence to oral chemotherapy.患者对口服化疗药物依从性相关障碍的看法。
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Characteristics of oncology clinical trials: insights from a systematic analysis of ClinicalTrials.gov.肿瘤学临床试验的特征:来自 ClinicalTrials.gov 的系统分析见解。
JAMA Intern Med. 2013 Jun 10;173(11):972-9. doi: 10.1001/jamainternmed.2013.627.
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Methods to improve recruitment to randomised controlled trials: Cochrane systematic review and meta-analysis.提高随机对照试验招募效果的方法:Cochrane 系统评价和荟萃分析。
BMJ Open. 2013 Feb 7;3(2). doi: 10.1136/bmjopen-2012-002360. Print 2013.
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Attrition rates, reasons, and predictive factors in supportive care and palliative oncology clinical trials.支持性护理和肿瘤姑息治疗临床试验中的脱落率、原因和预测因素。
Cancer. 2013 Mar 1;119(5):1098-105. doi: 10.1002/cncr.27854. Epub 2012 Nov 6.