Charlson F J, Lee Y Y, Diminic S, Whiteford H
School of Public Health, University of Queensland, Brisbane, Queensland, Australia.
Queensland Centre for Mental Health Research, Brisbane, Queensland, Australia.
Glob Ment Health (Camb). 2016 Mar 7;3:e8. doi: 10.1017/gmh.2016.4. eCollection 2016.
Epidemiological models are frequently utilised to ascertain disease prevalence in a population; however, these estimates can have wider practical applications for informing targeted scale-up and optimisation of mental health services. We explore potential applications for a conflict-affected population, Syria.
We use prevalence estimates of major depression and post-traumatic stress disorder (PTSD) in conflict-affected populations as inputs for subsequent estimations. We use Global Burden of Disease (GBD) methodology to estimate years lived with a disability (YLDs) for depression and PTSD in Syrian populations. Human resource (HR) requirements to scale-up recommended packages of care for PTSD and depression in Syria over a 15-year period were modelled using the World Health Organisation mhGAP costing tool. Associated avertable burden was estimated using health benefit analyses.
The total number of cases of PTSD in Syria was estimated at approximately 2.2 million, and approximately 1.1 million for depression. An age-standardised major depression rate of 13.4 (95% UI 9.8-17.5) YLDs per 1000 Syrian population is estimated compared with the GBD 2010 global age-standardised YLD rate of 9.2 (95% UI 7.0-11.8). HR requirements to support a linear scale-up of services in Syria using the mhGAP costing tool demonstrates a steady increase from 0.3 FTE in at baseline to 7.6 FTE per 100 000 population after scale-up. Linear scale-up over 15 years could see 7-9% of disease burden being averted.
Epidemiological estimates of mental disorders are key inputs into determining disease burden and guiding optimal mental health service delivery and can be used in target populations such as conflict-affected populations.
流行病学模型经常被用于确定人群中的疾病患病率;然而,这些估计对于为精神卫生服务的有针对性扩大和优化提供信息具有更广泛的实际应用。我们探讨了其在受冲突影响的叙利亚人群中的潜在应用。
我们将受冲突影响人群中重度抑郁症和创伤后应激障碍(PTSD)的患病率估计值作为后续估计的输入。我们使用全球疾病负担(GBD)方法来估计叙利亚人群中抑郁症和PTSD的失能调整生命年(YLDs)。使用世界卫生组织mhGAP成本核算工具,对叙利亚在15年期间扩大PTSD和抑郁症推荐护理包所需的人力资源(HR)进行了建模。使用健康效益分析估计了相关的可避免负担。
叙利亚PTSD病例总数估计约为220万,抑郁症约为110万。估计每1000名叙利亚人口中年龄标准化的重度抑郁症YLD率为13.4(95%UI 9.8 - 17.5),而2010年全球疾病负担研究中年龄标准化的YLD率为9.2(95%UI 7.0 - 11.8)。使用mhGAP成本核算工具对叙利亚线性扩大服务所需的人力资源显示,从基线时的0.3全时当量稳步增加到扩大后每10万人口7.6全时当量。15年的线性扩大可能避免7 - 9%的疾病负担。
精神障碍的流行病学估计是确定疾病负担和指导最佳精神卫生服务提供的关键输入,可用于受冲突影响人群等目标人群。