Sezzano P, Raimondi A, Pessina A, Neri M G
Acta Virol. 1985 Jan;29(1):73-8.
We report studies on ten strains of Escherichia coli 0111:K58 isolated from children with acute diarrhea. Our results show that these E. coli strains do not produce the pathogenic factors of enterotoxic E. coli (ETEC) and are lysogenic for phages belonging to two groups that differ for host range, kinetics of thermal inactivation, antigenicity and morphology. These data support the hypothesis that these phages may in vivo contribute to reduction of the number of common E. coli strains by lytic infection favouring the development of the enteropathogenic strain of E. coli.
我们报告了对从患有急性腹泻的儿童中分离出的10株大肠杆菌O111:K58的研究。我们的结果表明，这些大肠杆菌菌株不产生肠毒素性大肠杆菌（ETEC）的致病因子，并且对属于两组的噬菌体具有溶原性，这两组噬菌体在宿主范围、热灭活动力学、抗原性和形态方面存在差异。这些数据支持了这样一种假设，即这些噬菌体可能在体内通过溶菌感染有助于减少常见大肠杆菌菌株的数量，从而有利于大肠杆菌肠道致病菌株的发展。
