Hennessy T P
Br J Surg. 1985 May;72(5):336-40. doi: 10.1002/bjs.1800720503.
The bulk of available evidence supports the view that Barrett's oesophagus is an acquired condition due to chronic gastro-oesophageal reflux. It is possible that a few cases are congenital. Barrett's oesophagus gives rise to severe stricture and ulceration and has a significant malignant potential. Treatment is designed to prevent reflux and, if possible, to reverse the metaplastic change. Dysplasia is of ominous significance and requires frequent careful surveillance.
大量现有证据支持这样一种观点，即巴雷特食管是一种由于慢性胃食管反流而导致的后天性疾病。少数病例可能是先天性的。巴雷特食管会导致严重的狭窄和溃疡，并且具有显著的恶变潜能。治疗旨在预防反流，如有可能，逆转化生改变。发育异常具有不祥的意义，需要频繁进行仔细监测。
