Hosseini Seyedeh Fatemeh, Aboudzadeh Mohammadreza, Sadeghi Mahdi, Ahmadi Teymourlouy Ahmad, Rostampour Malihe
Department of Physics, Payame Noor University, P.O. Box: 19395-3697, Tehran, Iran.
Radiation Application Research School, Nuclear Science and Technology Research Institute, P.O. Box: 11365-8486, Tehran, Iran.
Appl Radiat Isot. 2017 Sep;127:137-141. doi: 10.1016/j.apradiso.2017.05.024. Epub 2017 May 31.
Cu radioisotope is a beta particle-emitting nuclide used in radioimmunotherapy (RIT) as well as for imaging, tracer kinetic studies and dosimetry. Cu can be produced by bombarding Zn with deuterons. In this study, the physical yields of Cu via Zn(d,x)Cu reaction channel as well as via subreactions of Zn(d,2pn)Cu, Zn(d,2p)Cu, Zn(d,2p3n)Cu, Zn(d,x)Ni(T=21s)→Cu and Zn(d,x)Ni(T=21s)→Cu in the Zn target have been calculated by using the MCNPX-2.6, TALYS-1.8 and SRIM codes. Also, the total cross sections for production of Cu from Zn(d,x)Cu reaction channel in the energy range of 15-45MeV have been estimated by TALYS code. The best reaction to produce Cu radionuclide in a carrier free form was chosen with deuteron energy around 30MeV on Zn thick target. Good agreement between the calculated results and the experimental values shows that the employed methods can be used for prediction and production estimation in cyclotron.
铜放射性同位素是一种发射β粒子的核素，用于放射免疫疗法（RIT）以及成像、示踪动力学研究和剂量测定。铜可以通过用氘核轰击锌来产生。在本研究中，使用MCNPX - 2.6、TALYS - 1.8和SRIM代码计算了通过锌（d，x）铜反应通道以及通过锌靶中锌（d，2pn）铜、锌（d，2p）铜、锌（d，2p3n）铜、锌（d，x）镍（T = 21秒）→铜和锌（d，x）镍（T = 21秒）→铜的子反应产生铜的物理产额。此外，TALYS代码估计了在15 - 45MeV能量范围内锌（d，x）铜反应通道产生铜的总截面。选择在厚锌靶上用约30MeV的氘核能量以无载体形式产生铜放射性核素的最佳反应。计算结果与实验值之间的良好一致性表明，所采用的方法可用于回旋加速器中的预测和产量估计。
