细胞外囊泡在疟疾生物学和发病机制中的作用。
The role of extracellular vesicles in malaria biology and pathogenesis.
作者信息
Sampaio Natalia Guimaraes, Cheng Lesley, Eriksson Emily M
机构信息
Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
出版信息
Malar J. 2017 Jun 9;16(1):245. doi: 10.1186/s12936-017-1891-z.
In the past decade, research on the functions of extracellular vesicles in malaria has expanded dramatically. Investigations into the various vesicle types, from both host and parasite origin, has revealed important roles for extracellular vesicles in disease pathogenesis and susceptibility, as well as cell-cell communication and immune responses. Here, work relating to extracellular vesicles in malaria is reviewed, and the areas that remain unknown and require further investigations are highlighted.
在过去十年中，关于细胞外囊泡在疟疾中功能的研究急剧扩展。对源自宿主和寄生虫的各种囊泡类型的研究揭示了细胞外囊泡在疾病发病机制和易感性以及细胞间通讯和免疫反应中的重要作用。在此，对与疟疾中细胞外囊泡相关的工作进行综述，并强调了仍不清楚且需要进一步研究的领域。
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