McKay Joshua, Nagueh Sherif F
Department of Cardiology, Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, 6550 Fannin, Smith Tower 677, Houston, TX 77030, USA.
Department of Cardiology, Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, 6550 Fannin, Smith Tower 677, Houston, TX 77030, USA.
Interv Cardiol Clin. 2017 Jul;6(3):445-452. doi: 10.1016/j.iccl.2017.03.012. Epub 2017 Apr 21.
Hypertrophic cardiomyopathy is a commonly encountered inheritable cardiac disorder with variable phenotypic expression. Although most patients will have no or mild symptoms, 10% will develop heart failure symptoms refractory to medical management. This article discusses the mechanisms through which hypertrophic cardiomyopathy induces heart failure and how alcohol septal ablation can reverse each of these mechanisms to lead to clinical improvement.
肥厚型心肌病是一种常见的遗传性心脏疾病，具有可变的表型表达。虽然大多数患者没有症状或仅有轻微症状，但10%的患者会出现药物治疗难以控制的心力衰竭症状。本文讨论了肥厚型心肌病诱发心力衰竭的机制，以及酒精室间隔消融如何逆转这些机制以实现临床改善。
