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[脓毒症与脓毒性休克:脓毒症-3之后的概述以及临床医生对危重症患者尸检的要求]

[Sepsis and septic shock : Overview after sepsis-3 and the requirements of the clinician regarding the autopsy of critically ill patients].

作者信息

Müller-Redetzky H

机构信息

Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.

出版信息

Pathologe. 2017 Sep;38(5):365-369. doi: 10.1007/s00292-017-0301-1.

DOI:10.1007/s00292-017-0301-1
PMID:28600707
Abstract

Sepsis and septic shock are frequent conditions of patients in the intensive care unit. Recent guidelines adjusted the diagnostic criteria for sepsis and septic shock as well as the recommendations for sepsis treatment, which together is important for the intensivist as well as for the pathologist. Patients who die from septic shock despite invasive and intense therapies display various pathological findings that have to be placed in a reasonable clinical context, which is challenging for the pathologist without close cooperation with the former caring clinician. This short review gives an overview of recent definitions, the pathophysiology and treatment recommendations for sepsis and septic shock and discusses the importance of interdisciplinary cooperation between the pathologist and intensivist in the autopsy of a patient.

摘要

脓毒症和脓毒性休克是重症监护病房患者的常见病症。近期指南调整了脓毒症和脓毒性休克的诊断标准以及脓毒症治疗建议,这对重症监护医生和病理学家都很重要。尽管接受了侵入性和强化治疗,但死于脓毒性休克的患者仍表现出各种病理特征,必须将其置于合理的临床背景中,这对于没有与之前的主治医生密切合作的病理学家来说具有挑战性。这篇简短综述概述了脓毒症和脓毒性休克的最新定义、病理生理学及治疗建议,并讨论了病理学家与重症监护医生在患者尸检中进行跨学科合作的重要性。

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Med Klin Intensivmed Notfmed. 2024 Mar;119(2):123-128. doi: 10.1007/s00063-023-01037-4. Epub 2023 Jun 28.
2
Post-Mortem Examination as a Quality Improvement Instrument.死后检查作为一种质量改进工具。
Dtsch Arztebl Int. 2018 Sep 28;115(39):653-658. doi: 10.3238/arztebl.2018.0653.
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[Consequences of autopsies for the living : Causes of death in the clinical diagnosis "septic and toxic shock"].

本文引用的文献

1
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.拯救脓毒症运动:脓毒症与脓毒性休克管理国际指南:2016版
Crit Care Med. 2017 Mar;45(3):486-552. doi: 10.1097/CCM.0000000000002255.
2
Hospital Incidence and Mortality Rates of Sepsis.脓毒症的医院发病率和死亡率
Dtsch Arztebl Int. 2016 Mar 11;113(10):159-66. doi: 10.3238/arztebl.2016.0159.
3
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).《脓毒症及脓毒性休克第三次国际共识定义(脓毒症-3)》
尸检对生者的影响:临床诊断“感染性和中毒性休克”中的死亡原因
Pathologe. 2017 Sep;38(5):370-379. doi: 10.1007/s00292-017-0305-x.
JAMA. 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287.
4
Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).制定脓毒性休克的新定义并评估新的临床标准:用于第三次脓毒症和脓毒性休克国际共识定义(Sepsis-3)。
JAMA. 2016 Feb 23;315(8):775-87. doi: 10.1001/jama.2016.0289.
5
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).脓毒症临床标准评估:针对《脓毒症及脓毒性休克第三次国际共识定义》(Sepsis-3)。
JAMA. 2016 Feb 23;315(8):762-74. doi: 10.1001/jama.2016.0288.
6
Systemic inflammatory response syndrome criteria in defining severe sepsis.全身性炎症反应综合征标准在严重脓毒症中的应用。
N Engl J Med. 2015 Apr 23;372(17):1629-38. doi: 10.1056/NEJMoa1415236. Epub 2015 Mar 17.
7
Trial of early, goal-directed resuscitation for septic shock.早期目标导向性复苏治疗脓毒性休克的试验。
N Engl J Med. 2015 Apr 2;372(14):1301-11. doi: 10.1056/NEJMoa1500896. Epub 2015 Mar 17.
8
Goal-directed resuscitation for patients with early septic shock.目标导向性复苏治疗早期感染性休克患者。
N Engl J Med. 2014 Oct 16;371(16):1496-506. doi: 10.1056/NEJMoa1404380. Epub 2014 Oct 1.
9
A randomized trial of protocol-based care for early septic shock.一项基于方案的早期脓毒性休克护理的随机试验。
N Engl J Med. 2014 May 1;370(18):1683-93. doi: 10.1056/NEJMoa1401602. Epub 2014 Mar 18.
10
Dynamics of pulmonary endothelial barrier function in acute inflammation: mechanisms and therapeutic perspectives.急性炎症中肺内皮屏障功能的动态变化:机制与治疗前景
Cell Tissue Res. 2014 Mar;355(3):657-73. doi: 10.1007/s00441-014-1821-0. Epub 2014 Mar 6.