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[脓毒症与脓毒性休克:脓毒症-3之后的概述以及临床医生对危重症患者尸检的要求]

[Sepsis and septic shock : Overview after sepsis-3 and the requirements of the clinician regarding the autopsy of critically ill patients].

作者信息

Müller-Redetzky H

机构信息

Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.

出版信息

Pathologe. 2017 Sep;38(5):365-369. doi: 10.1007/s00292-017-0301-1.

Abstract

Sepsis and septic shock are frequent conditions of patients in the intensive care unit. Recent guidelines adjusted the diagnostic criteria for sepsis and septic shock as well as the recommendations for sepsis treatment, which together is important for the intensivist as well as for the pathologist. Patients who die from septic shock despite invasive and intense therapies display various pathological findings that have to be placed in a reasonable clinical context, which is challenging for the pathologist without close cooperation with the former caring clinician. This short review gives an overview of recent definitions, the pathophysiology and treatment recommendations for sepsis and septic shock and discusses the importance of interdisciplinary cooperation between the pathologist and intensivist in the autopsy of a patient.

摘要

脓毒症和脓毒性休克是重症监护病房患者的常见病症。近期指南调整了脓毒症和脓毒性休克的诊断标准以及脓毒症治疗建议,这对重症监护医生和病理学家都很重要。尽管接受了侵入性和强化治疗,但死于脓毒性休克的患者仍表现出各种病理特征,必须将其置于合理的临床背景中,这对于没有与之前的主治医生密切合作的病理学家来说具有挑战性。这篇简短综述概述了脓毒症和脓毒性休克的最新定义、病理生理学及治疗建议,并讨论了病理学家与重症监护医生在患者尸检中进行跨学科合作的重要性。

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